Publication
2023
- A. Roth, A. Krishnakumar, R. McCain, K. Maruthamuthu, M. McIntosh, Y. Chen, A. Cox, J. Hopf, N. Amber, M. N. Seleem, R. Rahimi. (2023). Biocompatibility and Safety Assessment of Combined Topical Ozone and Antibiotics for Treatment of Infected Wounds. ACS Biomaterials Science & Engineering. https://pubs.acs.org/doi/10.1021/acsbiomaterials.2c01548
- D. Liu; X. Bai, H. Helmick, M. Samaddar, M. Amalaradjou, X. Li, S. Tenguria, N. Gallina, L. Xu, R. Drolia, U. Aryal, G. Moreira, M. Hust, M.N. Seleem, J. Kokini, R. Ostafe, A. Cox, A. K. Bhunia. (2023). Cell Surface Anchoring of Listeria Adhesion Protein on L. monocytogenes is Fastened by Internalin B for Pathogenesis. Cell Reports. 42(5):112515. https://doi.org/10.1016/j.celrep.2023.112515
- Elgammal, Y., Salama, E. A., & Seleem, M. N. (2023). Atazanavir Resensitizes Candida auris to Azoles. Antimicrobial Agents and Chemotherapy, e01631-22. https://doi.org/10.1128/aac.01631-22
- NS Abutaleb, A Shrinidhi, AB Bandara, M. N Seleem, DP Flaherty (2023). Evaluation of 1, 3, 4-Thiadiazole Carbonic Anhydrase Inhibitors for Gut Decolonization of Vancomycin-Resistant Enterococci. ACS Medicinal Chemistry Letters. March 21, 2023. https://doi.org/10.1021/acsmedchemlett.3c00032
- HTN El-Din, MM Elsebaie, NS Abutaleb, AM Kotb, AS Attia, M. N. Seleem, A. Mayhoub. (2023). Expanding the structure–activity relationships of alkynyl diphenylurea scaffold as promising antibacterial agents. RSC Medicinal Chemistry 14 (2), 367-377. https://doi.org/10.1039/D2MD00351A
- S. Bose, C. N. Steussy, D. López-Pérez, T. Schmidt, S. C. Kulathunga, M. N. Seleem, M. Lipton, A. D. Mesecar, V. W. Rodwell & C. V. Stauffacher. (2023). Targeting Enterococcus faecalis HMG-CoA reductase with a non-statin inhibitor. Nature Communications biology 6, Article number: 360 (2023). https://doi.org/10.1038/s42003-023-04639-y
- E. M.E. Dokla, N. S. Abutaleb, S. N. Milik, E. Kindil, O. Assem, Y. Elgammal, M. Nasr, M. McPhillie, K. Abouzid, M N. Seleem, P. Imming, and M. Adel. (2023). SAR investigation and optimization of benzimidazole-based derivatives as antimicrobial agents against Gram-negative bacteria. European Journal of Medicinal Chemistry. Volume 247, 5 February 2023, 115040. https://doi.org/10.1016/j.ejmech.2022.115040
- A. Marapaka, A. Nocentini, M. S. Youse, W. An, K. J. Holly, C. Das, R. Yadav, M. N. Seleem, C. T. Supuran, and D. P. Flaherty. (2023). Structural Characterization of Thiadiazolesulfonamide Inhibitors Bound to Neisseria gonorrhoeae α-Carbonic Anhydrase. ACS Med. Chem. Lett. 2023, 14, 1, 103-109. https://doi.org/10.1021/acsmedchemlett.2c00471
- A. M. Sayed, N. S. Abutaleb, A. Kotb, H. G. Ezzat, M. N. Seleem, A. S. Mayhoub, M. M. Elsebaie. (2023). Arylpyrazole as selective anti-enterococci; synthesis and biological evaluation of novel derivatives for their antimicrobial efficacy. J Heterocyclic Chem.2023;60:134–144. https://doi.org/10.1002/jhet.4570
2022
- Pal R, Seleem MN (2022) Discovery of a novel natural product inhibitor of Clostridioides difficile with potent activity in vitro and in vivo. PLoS ONE 17(8): e0267859. https://doi.org/10.1371/journal.pone.0267859
- C. W. Karanja, N. Naganna, N. S. Abutaleb, N. Dayal, K. Onyedibe, U. Aryal, M. N. Seleem and H. O. Sintim. (2022). Isoquinoline Antimicrobial Agent: Activity against Intracellular Bacteria and Effect on Global Bacterial Proteome. Molecules 2022, 27(16), 5085; https://doi.org/10.3390/molecules27165085
- Roth, M. Maruthamuthu, S. Nejati, A. Krishnakumar, V. Selvamani, S. Sedaghat, J. Nguyen, M. N. Seleem & R. Rahimi. (2022). Wearable adjunct ozone and antibiotic therapy system for treatment of Gram-negative dermal bacterial infection. Scientific Reports, 12: 13927 (2022). https://doi.org/10.1038/s41598-022-17495-3
- W. An, K. J Holly, A. Nocentini, R. Imhoff, C. Hewitt, N. S. Abutaleb, X. Cao, M. N. Seleem, C. T. Supuran, D. P. Flaherty. (2022). Structure-activity relationship studies for inhibitors for vancomycin-resistant Enterococcus and human carbonic anhydrases. Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 1838-1844. https://doi.org/10.1080/14756366.2022.2092729
- M. Elsebaie, H. Nour Din, N. S. Abutaleb, A. Abuelkhir, H. Liang, A. Attia, M N Seleem and A. Mayhoub. (2022). Exploring the Structure-Activity Relationships of Diphenylurea as an Antibacterial Scaffold Active against Methicillin- and Vancomycin-Resistant Staphylococcus aureus. Eur J Med Chem 2022, EJMECH-D-21-03184. https://doi.org/10.1016/j.ejmech.2022.114204
- R. Pal, A. Athamneh, R. Deshpande, J. Ramirez, K. Adu, P. Muthuirulan, S. Pawar, M. Biazzo, Y. Apidianakis, U. Sundekilde, C. Fuente-Nunez, M. Martens, G. Tegos, M N Seleem. (2022). Probiotics: insights and new opportunities for Clostridioides difficile intervention. Critical Reviews in Microbiology. 2022.2072705. https://doi.org/10.1080/1040841X.2022.2072705
- H. Oliveira, R. Castelli, L. Alves, J. Nosanchuk, E. Salama, M N. Seleem, M. Rodrigues. (2022). Identification of 4 compounds from the Pharmakon library with antifungal activity against Candida auris and species of Cryptococcus. Medical Mycology. myac033. https://doi.org/10.1093/mmy/myac033
- G. Naclerio, N. Abutaleb, K. Onyedibe, C. Karanja, H. Eldesouky, H. Liang, A. Dieterly, U. Aryal, T. Lyle, M. N. Seleem, H. O Sintim. 2022. Mechanistic Studies and In Vivo Efficacy of an Oxadiazole-Containing Antibiotic . Journal of Medicinal Chemistry. 2022, 65, 9, 6612–6630. https://doi.org/10.1021/acs.jmedchem.1c02034
- AEM Elhassanny, NS Abutaleb, MN Seleem. (2022). Auranofin exerts antibacterial activity against Neisseria gonorrhoeae in a female mouse model of genital tract infection. Plos one 17 (4), e0266764. https://doi.org/10.1371/journal.pone.0266764
- M Zhang, M.N. Seleem, JX Cheng. (2022). Rapid Antimicrobial Susceptibility Testing by Stimulated Raman Scattering Imaging of Deuterium Incorporation in a Single Bacterium. JoVE (Journal of Visualized Experiments), e62398. http://doi.org/10.3791/62398
- S. Giovannuzzi, N. S. Abutaleb, C. S. Hewitt, F. Carta, A. Nocentini, M N Seleem, D. Flaherty, C. T Supuran. (2022). Dithiocarbamates effectively inhibit the α-carbonic anhydrase from Neisseria gonorrhoeae. Journal of Enzyme Inhibition and Medicinal Chemistry. 2022, VOL. 37, NO. 1, 1-8. https://doi.org/10.1080/14756366.2021.1988945
- N. S. Abutaleb, A. Elhassanny, A. Nocentini, C. Hewitt, A. Elkashif, B. Cooper, C. T Supuran, M N Seleem, D. Flaherty. (2022). Repurposing FDA-approved sulphonamide carbonic anhydrase inhibitors for treatment of Neisseria gonorrhoeae. Journal of Enzyme Inhibition and Medicinal Chemistry. 2022, VOL. 37, NO. 1, 51-61. https://doi.org/10.1080/14756366.2021.1991336
- N. S. Abutaleb, A. Elhassanny, M N Seleem. (2022). In vivo efficacy of acetazolamide in a mouse model of Neisseria gonorrhoeae infection. 2022.105454. https://doi.org/10.1016/j.micpath.2022.105454
2021
- M. Hagras, N. S. Abutaleb, A. M Sayed, E. A. Salama, M N Seleem, A. Mayhoub. (2021). Evaluation of bisphenylthiazoles as a promising class for combating multidrug-resistant fungal infections. Plos one e0258465. https://doi.org/10.1371/journal.pone.0258465
- Z. Iqbal, H. Hussain, M N Seleem, M. Shabbir, A. Sattar, A.Aqib, X. Kuang, A. Ihsan, H. Hao. (2021). RNA-seq-based transcriptome analysis of a cefquinome-treated, highly resistant, and virulent MRSA strain. Microbial Pathogenesis. 2021 Nov;160:105201. https://doi.org/10.1016/j.micpath.2021.105201
- H. Mohammad, N. S. Abutaleb, A. M. Dieterly, L. T. Lyle & M. N. Seleem. (2021). Investigating auranofin for the treatment of infected diabetic pressure ulcers in mice and dermal toxicity in pigs. Scientific Reports 11, 10935 (2021). https://doi.org/10.1038/s41598-021-90360-x
- M. Hamed and M. N. Seleem. (2021). Evaluation of Short Synthetic Antimicrobial Peptides against Staphylococcus pseudintermedius. Journal of Advanced Veterinary Research 11,2,(2021) 69-72. https://advetresearch.com/index.php/AVR/article/view/652/459
- R. Pal, M. Dai, & M. N. Seleem. (2021). High-throughput screening identifies a novel natural product-inspired scaffold capable of inhibiting Clostridioides difficile in vitro. Scientific Reports 11, 10913 (2021). https://doi.org/10.1038/s41598-021-90314-3
- H. Hussain, A. Aqib, M.N. Seleem , M. Shabbir, H. Hao, Z. Iqbal, M. Kulyar, T. Zaheer , K. Li. (2021). Genetic basis of molecular mechanisms in β-lactam resistant gram-negative bacteria. Jun10;158:105040. Micro. Patho. 158, 2021, 105040. https://doi.org/10.1016/j.micpath.2021.105040
- Woodhouse, S. Nejati, V. Selvamani, H. Jiang, S. Chittiboyina, J. Grant, Z. Mutlu, J. Waimin, N. S. Abutaleb, M. N. Seleem, R. Rahimi (2021). Flexible Microneedle Array Patch for Chronic Wound Oxygenation and Biofilm Eradication ACS Appl. Bio Mater. 2021, 4, 7, 5405–5415. https://doi.org/10.1021/acsabm.1c00087
- S. A Yuk, H. Kim, N. S. Abutaleb, A. M. Dieterly, M. S. Taha, M. D. Tsifansky, L. T. Lyle, M. N. Seleem, Y. Yeo. (2021). Nanocapsules modify membrane interaction of polymyxin B to enable safe systemic therapy of Gram-negative sepsis. Science Advances 7 (32), eabj1577. http://doi.org/10.1126/sciadv.abj1577
- D P Flaherty, M N Seleem, C T Supuran. (2021). Bacterial carbonic anhydrases: underexploited antibacterial therapeutic targets. Future Medicinal Chemistry fmc-2021-0207. https://doi.org/10.4155/fmc-2021-0207
- N.S. Abutaleb, A. Elhassanny, D.P. Flaherty, M.N. Seleem. (2021). In vitro and in vivo activities of the carbonic anhydrase inhibitor, dorzolamide, against vancomycin-resistant enterococci. PeerJ 9:e11059. https://doi.org/10.7717/peerj.11059
- N.S. Abutaleb, and M.N. Seleem. (2021). In vivo efficacy of auranofin in a hamster model of Clostridioides difficile infection. Scientific Reports, 11: 7093 (2021). https://doi.org/10.1038/s41598-021-86595-3
- C. Hewitt, N.S. Abutaleb, A. Elhassanny, A. Nocentini, X. Cao, D. Amos, M. Youse, K. Holly, A. Marapaka, W. An, J. Kaur, A. Krabill, A. Elkashif, Y. Elgammal, A. L Graboski, C. T. Supuran, M. N. Seleem, D. P. Flaherty. (2021). Structure–Activity Relationship Studies of Acetazolamide-Based Carbonic Anhydrase Inhibitors with Activity against Neisseria gonorrhoeae. ACS Infectious Diseases https://doi.org/10.1021/acsinfecdis.1c00055
- C. Ghosh, S. Varela‐Aramburu, H. E Eldesouky, S. Hossainy, M. N. Seleem, T. Aebischer, P. H Seeberger. (2021). Non‐Toxic Glycosylated Gold Nanoparticle‐Amphotericin B Conjugates Reduce Biofilms and Intracellular Burden of Fungi and Parasites. Advanced Therapeutics, 2021,2000293. https://doi.org/10.1002/adtp.202000293
- M. Zhang, W. Hong, N. S. Abutaleb, J. Li, P. Dong, C. Zong, P. Wang, M. N. Seleem, J. Cheng. (2021). Rapid determination of antimicrobial susceptibility by stimulated Raman scattering imaging of D2O metabolic incorporation in a single bacterium. International Society for Optics and Photonics, 11656; 116560B. https://doi.org/10.1002/advs.202001452
- E. Coscia, N. Abutaleb, B. Hostette, M. N. Seleem, G. Breur, R. McCain, C. Crain, O. Slaby, M. Capoor, A. McDowell, F. Ahmed, V. Vijayanpillai, S. Narayanan and M. Coscia (2021). Sheep as a Potential Model of Intradiscal Infection by the Bacterium Cutibacterium acnes. Veterinary Sciences 8(48):48. https://doi.org/10.3390/vetsci8030048
- G. A Naclerio, N. S Abutaleb, M. Alhashimi, M. N. Seleem, H. O Sintim. (2021). N-(1, 3, 4-Oxadiazol-2-yl) Benzamides as Antibacterial Agents against Neisseria gonorrhoeae. International journal of molecular sciences. 22;5;2427. https://doi.org/10.3390/ijms22052427
- N.S. Abutaleb, A. Elkashif, D.P. Flaherty, M.N. Seleem. (2021). In vivo antibacterial activity of acetazolamide. Antimicrobial Agents and Chemotherapy 10.1128/AAC.01715-20. https://doi.org/10.1128/AAC.01715-20
- H. E. Eldesouky, E. A. Salama, N. A. Lanman, T. R. Hazbun, M.N. Seleem. (2021). Potent Synergistic Interactions between Lopinavir and Azole Antifungal Drugs against Emerging Multidrug-Resistant Candida auris. Antimicrobial Agents and Chemotherapy. 2021:65:1. https://doi.org/10.1128/AAC.00684-20
- H. Mohammad, N. S. Abutaleb, A. M. Dieterly, L. T. Lyle, M.N. Seleem. (2021). Evaluation of ebselen in resolving a methicillin-resistant Staphylococcus aureus infection of pressure ulcers in obese and diabetic mice. PLoS ONE 16(2): e024750. https://doi.org/10.1371/journal.pone.0247508
2020
- Hagras M, Abutaleb NS, N. Elhosseiny, T. Abdelghany, M. N. Seleem, Mayhoub AS. (2020). Development of biphenylthiazoles exhibiting improved pharmacokinetics and potent activity against intracellular Staphylococcus aureus. 2020, 6, 11, 2887–2900. ACS Infectious Diseases IF= 4.614. https://doi.org/10.1021/acsinfecdis.0c00137
- G. Naclerio, N. Abutaleb, D. Li, M. N. Seleem, H. Sintim.(2020). Ultrapotent inhibitor of Clostridioides difficile growth, which suppresses recurrence in vivo. 2020, 63, 20, 11934–11944. Journal of Medicinal Chemistry. IF=6.02. https://doi.org/10.1021/acs.jmedchem.0c01198
- A. V. Morales-de-Echegaray, L. Lin, B. Sivasubramaniam, A. Yermembetova, Q. Wang, Abutaleb NS, M. N. Seleem. & A. Wei. (2020). Antimicrobial Photodynamic Activity of Gallium-Substituted Haemoglobin on Silver Nanoparticles. 2020,12, 21734-21742. Nanoscale. IF=6.97. https://doi.org/10.1039/C9NR09064A
- H. Eldesouky, E. Salama, N. Lanman, T. Hazbun, M. N. Seleem. (2020). Potent synergistic interactions between lopinavir and azole antifungal drugs against emerging multidrug-resistant Candida auris. 10.1128/AAC.00684-20. Antimicrob Agents Chemother. IF= 4.715. https://doi.org/10.1128/AAC.00684-20
- A. Abdelkhalek and M. N. Seleem. (2020). Repurposing the Veterinary Antiprotozoal Drug Ronidazole for the Treatment of Clostridioides difficile Infection. 2020 Oct 9;106188. International Journal of Antimicrobial Agents. IF=4.62. https://doi.org/10.1016/j.ijantimicag.2020.106188
- J. Song, S. Malwal, N. Baig, L. Schurig-Briccio, Z. Gao, G. Vaidya, K. Yang, N. Abutaleb, M. N. Seleem, R. Gennis, T., V. Pogorelov, E. Oldfield, X. Feng. (2020). Discovery of Prenyltransferase Inhibitors with In vitro and In vivo Antibacterial Activity. 2020, 6, 11, 2979–2993. ACS Infectious Diseases IF= 4.614. https://doi.org/10.1021/acsinfecdis.0c00472
- H. Eldesouky, N. Lanman, T. Hazbun, M. N. Seleem. (2020). Aprepitant, an antiemetic agent, interferes with metal ion homeostasis of Candida auris and displays potent synergistic interactions with azole drugs. Virulence 2020; 11(1): 1466–1481. IF=5.47. https://doi.org/10.1080/21505594.2020.1838741
- M. G. Elnaggar, H. E. Eldesouky, Y. Pei, J. Park, H. Mohammad, Y. A. Hegazy, H. M. Tawfeek, A. A. Abdel-Rahman, A. E. Aboutaleb, M. N. Seleem, Y. Yeo. (2020). Antibacterial nanotruffles for treatment of intracellular bacterial infection. Journal: Biomaterials. August 2020, 120344. IF= 10.31. https://doi.org/10.1016/j.biomaterials.2020.120344
- W. Zhou, A. Hsu, T. Wang, J. Jefferies, H. Mohammad, Y. Liu, Z. Luo, D. Umulis, M. N. Seleem, Q. Deng. (2020). Mitofusin 2 regulates neutrophil adhesive migration and the actin cytoskeleton. Journal of Cell Science. jcs.248880 doi: 10.1242/jcs.248880. IF= 4.57. https://doi.org/10.1242/jcs.248880
- Kaur J, Cao X, Abutaleb NS, Elkashif A, Graboski AL, Tarawneh AH, Bhardwaj A, AbdelKhalek A, M. N. Seleem, Flaherty DP. (2020). Optimization of Acetazolamide-Based Scaffold as Potent Inhibitors of Vancomycin-Resistant Enterococcus. J. Med. Chem. Jul 8, 28, 2020. IF= 6.02. https://doi.org/10.1021/acs.jmedchem.0c00734
- H. Hamann, Abutaleb NS, R. Pal, M. N. Seleem, P. V. Ramachandran. (2020). Gamma-Diaryl alpha-methylene-gamma-butyrolactones as potent antibacterials against methicillin-resistant Staphylococcus aureus. Bioorganic Chemistry. 28 August 2020, 104183. IF= 4.8. https://doi.org/10.1016/j.bioorg.2020.104183
- M. Zhang, W. Hong, N. Abutaleb, J. Li, P. Dong, C. Zong, P. Wang, M. N. Seleem, Ji-Xin Cheng. (2020). Rapid Determination of Antimicrobial Susceptibility by Stimulated Raman Scattering Imaging of D2O Metabolic Incorporation in a Single Bacterium. Advanced Science. 2020,2001452. IF= 15.80. https://doi.org/10.1002/advs.202001452
- M. Magana, M. Pushpanathan, A. Santos, L. Leanse, M. Fernandez, A. Ioannidis, M. Giulianotti, Y. Apidianakis, S. Bradfute, A. Ferguson, A. Cherkasov, M. N Seleem, C. Pinilla, C. Fuente-Nunez, T. Lazaridis, T. Dai, R. Houghten, R. Hancock, G. Tegos. (2020). The value of antimicrobial peptides in the age of resistance. The Lancet Infectious Diseases 3099(20)30327-3. IF= 71·421. https://doi.org/10.1016/S1473-3099(20)30327-3
- N. S. Abutaleb & M. N. Seleem. (2020). Antivirulence activity and in vivo efficacy of auranofin against vancomycin-resistant enterococci (VRE). International Journal of Antimicrobial Agents. 55(3):105828 . IF= 4.6. https://doi.org/10.1016/j.ijantimicag.2019.10.009
- A. Mancy, N. S. Abutaleb, M. Elsebaei, A. Yousef, A. Kotb, A. Ali, J. AbdelAleem, H. Mohammed, M. N. Seleem & A. Mayhoub. (2020). Balancing Physicochemical Properties of Phenylthiazole Compounds with Antibacterial Potency by Modifying the Lipophilic Side Chain. ACS Infectious Diseases. 6(1), pp. 80-90. IF= 4.91. https://doi.org/10.1021/acsinfecdis.9b00211
- J. Hui, P. Dong, L. Liang, T. Mandal, J. Li, C. Ulloa, Y. Zhan, S. Jusuf, C. Zong, M. N. Seleem, G. Liu, Q. Cui, J. Cheng. (2020). Photo-Disassembly of Membrane Microdomains Revives Conventional Antibiotics against MRSA. Advanced Science 1903117 IF= 15.80. https://doi.org/10.1002/advs.201903117
- V. Selvamani, A. Zareei, A. Elkashif, M. K. Maruthamuthu, S. Chittiboyina, D. Delisi, Z. Li, L. Cai, V. G. Pol, M. N. Seleem, R. Rahimi. (2020). Hierarchical Micro/Mesoporous Copper Structure with Enhanced Antimicrobial Property via Laser Surface Texturing. Advanced Material Interface. 1901890. IF= 4.85. https://doi.org/10.1002/admi.201901890
- Hagras, M., Salama, E.A., Sayed, A.M M. N. Seleem & A. Mayhoub. (2020). Oxadiazolylthiazoles as novel and selective antifungal agents. European Journal of Medicinal Chemistry 189,112046 IF= 4.81. https://doi.org/10.1016/j.ejmech.2020.112046
- Dokla, E.M.E., Abutaleb, N.S., Milik, S.N., Abouzid, K.A.M., M. N. Seleem. (2020). Development of benzimidazole-based derivatives as antimicrobial agents and their synergistic effect with colistin against gram-negative bacteria. European Journal of Medicinal Chemistry 186,111850 IF= 4.81. https://doi.org/10.1016/j.ejmech.2019.111850
- Vadlamani, R.A., Dhanabal, A., Detwiler, D.A., R. Pal, M. N. Seleem., Garner, A.L. (2020). Nanosecond electric pulses rapidly enhance the inactivation of Gram-negative bacteria using Gram-positive antibiotics. Applied Microbiology and Biotechnology. Volume 104, Issue 5, 1 March 2020, Pages 2217-2227. IF= 3.67. https://doi.org/10.1007/s00253-020-10365-w
- Naclerio GA, Abutaleb NS, Onyedibe KI, M. N. Seleem and Sintim HO. (2020). Potent trifluoromethoxy, trifluoromethylsulfonyl, trifluoromethylthio and pentafluorosulfanyl containing (1,3,4-oxadiazol-2-yl) benzamides against drug-resistant Gram-positive bacteria. RSC Med. Chem. 2020,11, 102-110 IF= 3.049 https://doi.org/10.1039/C9MD00391F
- Hammad S., Abutaleb NS, D. Li, I. Ramming, A. Shekhar, Abdel-Halim M., E. Elrazaz, M. N. Seleem, U. Bilitewski, K. Abouzid, E. El-Hossary. (2020). Synthesis and Antimicrobial evaluation of New Halogenated 1,3-Thiazolidin-4-ones. Bioorg Chem., 103517. IF= 3.9. https://doi.org/10.1016/j.bioorg.2019.103517
- Hosny Y, Abutaleb NS, Omara M, Alhashimi M, Elsebaei MM, Elzahabi HS, N. Seleem & A. Mayhoub. (2020). Modifying the lipophilic part of phenylthiazole antibiotics to control their drug-likeness. Eur J Med Chem 2020, 185:111830. IF= 4.83. https://doi.org/10.1016/j.ejmech.2019.111830
- H. Eldesouky, E. Salam, L. Xiaoyan, H. Mohammad, T. Hazbun, A. Mayhoub & M. N. Seleem. (2020). Repurposing approach identifies pitavastatin as a potent azole chemosensitizing agent effective against azole-resistant Candida species. Scientific reports 10 (1), 1-12 IF= 4.25. https://doi.org/10.1038/s41598-020-64571-7
- C. Ghosh, A. AbdelKhalek, H. Mohammad, M. N. Seleem & J. Haldar. (2020) Aryl-alkyl-lysines: Novel agents for treatment of C. difficile infection. Scientific reports 10 (1), 1-7 IF= 4.25. https://doi.org/10.1038/s41598-020-62496-9
- A. Abdelkhalek, H. Mohammad, A. Mayhoub & M. N. Seleem. (2020). Screening for potent and selective anticlostridial leads among FDA-approved drugs. The Journal of Antibiotics 73 (6), 392-409. IF= 2.60. https://doi.org/10.1038/s41429-020-0288-3
- Young Jin Seong, A. Mayhoub, H. Mohammad & M. N. Seleem. (2020). Repurposing fenamic acids drugs to combat multidrug-resistant Neisseria gonorrhoeae. Antimicrobial Agents and Chemotherapy. 10.1128/AAC.02206-19. IF= 4.60. https://doi.org/10.1128/AAC.02206-19
- H. Eldesouky, E. Salam, T. Hazbun, A. Mayhoub & M. N. Seleem. (2020). Ospemifene displays broad-spectrum synergistic interactions with itraconazole through potent interference with fungal efflux activities. Scientific reports 10 (6089) IF= 4.25. https://doi.org/10.1038/s41598-020-62976-y
- Abutaleb NS, M. N. Seleem. (2020). Repurposing the antiamoebic drug diiodohydroxyquinoline for treatment of Clostridioides difficile infections. Antimicrob Agents Chemother. 64 (6) IF= 4.715. https://doi.org/10.1128/AAC.02115-19
- R. Pal and M. N. Seleem (2020). Screening of Natural Products and Approved Oncology Drug Libraries for Activity against Clostridioides difficile. Scientific Reports. 10 (1), 1-8. IF= 4.25. https://doi.org/10.1038/s41598-020-63029-0
- Mohammad, H., N. Abutaleb, M. N. Seleem. (2020). Auranofin Rapidly Eradicates Methicillin-resistant Staphylococcus aureus (MRSA) in an Infected Pressure Ulcer Mouse Model. Scientific Reports. 10 (1), 1-8 IF= 4.25. https://doi.org/10.1038/s41598-020-64352-2
- A. Elkashif and M. N. Seleem. (2020). Investigation of auranofin and gold-containing analogues antibacterial activity against multidrug-resistant Neisseria gonorrhoeae. Scientific Reports. 10 (1), 1-9. IF= 4.25. https://doi.org/10.1038/s41598-020-62696-3
- Thomas A. Dietsche, Eldesouky HE, M. N. Seleem, and Jean Chmielewski (2020). Targeting Intracellular Pathogenic Bacteria Through N-Terminal Modification of Cationic Amphiphilic Polyproline Helices. The Journal of Organic Chemistry. 2020, 85, 11, 7468–7475. IF= 4.8. https://doi.org/10.1021/acs.joc.0c00871
- Abutaleb NS, M. N. Seleem. (2020). Auranofin, at clinically achievable dose, protects mice and prevents recurrence from Clostridioides difficile infection. Scientific Reports 10 (1), 1-8. IF= 4.25. https://doi.org/10.1038/s41598-020-64882-9
- I. Shahin, Abutaleb NS, M. Alhashimi, A. Kassab, K..Mohamed, A. Taher, N. Seleem & A. Mayhoub. (2020). Evaluation of N-Phenyl-2-aminothiazoles for Treatment of Multi-Drug Resistant and Intracellular Staphylococcus aureus Infections. Eur J Med Chem 2020, 112497. IF= 4.83. https://doi.org/10.1016/j.ejmech.2020.112497
- A Roth, A. Elkashif, V. Selvamani, M. N. Seleem, B. Ziaie, R. Rahim. (2020). Wearable and Flexible Ozone Generating System for Treatment of Infected Dermal Wounds. Frontiers in Bioengineering and Biotechnology 8, 458. IF= 5.12. https://doi.org/10.3389/fbioe.2020.00458
2019
- A. Abdelkhalek, N. Abutaleb, H. Mohammad & M. N. Seleem. (2019). Antibacterial and antivirulence activities of auranofin against Clostridium difficile. International Journal of Antimicrobial Agents 53: 54-62. IF= 4.30. https://doi.org/10.1016/j.ijantimicag.2018.09.018
- S. Malwal, L. Chen, H. Hicks, F. Qu, W. Liu, A. Shillo, W. Law, J. Zhang, N. Chandnani, X. Han, Y. Zheng, C. Chen, R. Guo, A. AbdelKhalek, M. N. Seleem & E. Oldfield. (2019) Discovery of lipophilic bisphosphonates that target bacterial cell wall and quinone biosynthesis. Journal of Medicinal Chemistry. 62 (5), 2564-2581. IF= 6.25. https://doi.org/10.1021/acs.jmedchem.8b01878
- A. Kotb, N. S. Abutaleb, M. Hagras, A. Bayoumi, M. Mohamed, A. Moustafa, A. Ghiaty, M. N. Seleem & A. Mayhoub. (2019). tert-Butylphenylthiazoles with oxadiazole linker: A novel orally bioavailable class of antibiotics exhibiting antibiofilm activity. RSC Advances. 9 (12), 6770-6778. IF= 2.93. https://doi.org/10.1039/C8RA10525A
- P. Dong, H. Mohammad, X. Wang, J. Hui, J. Li, L. Liang, M. N. Seleem & Ji-Xin Cheng. (2019). Photolysis of staphyloxanthin in methicillin-resistant Staphylococcus aureus potentiates killing by reactive oxygen species. Advanced Science. 2019, 1900030. IF= 15.80. https://doi.org/10.1002/advs.201900030
- K. Kyei-Baffoura, H. Mohammad, M. N. Seleem & M. Dai. (2019). Second-generation aryl isonitrile compounds targeting multidrug-resistant Staphylococcus aureus. Bioorganic & Medicinal Chemistry. 27 (9), 1845-1854. IF= 2.9. https://doi.org/10.1016/j.bmc.2019.03.034
- M. Elsebaei, H. Mohammad, N. S. Abutaleb, A. Samir, A. Norvil, A. Michie, M. Gad, H. Gowher, M. N. Seleem & A. Mayhoub. (2019). Lipophilic efficient phenylthiazoles with potent undecaprenyl pyrophosphatase inhibitory activity. European Journal of Medicinal Chemistry. 175, 49-62. IF= 4.81. https://doi.org/10.1016/j.ejmech.2019.04.063
- H. Mohammad, K. Kyei-Baffoura, N. Abutaleb, M. Dai & M. N. Seleem (2019). An aryl isonitrile compound with an improved physicochemical profile that is effective in two mouse models of multidrug-resistant Staphylococcus aureus infection. Journal of global antimicrobial resistance. S2213-7165(19)30105-5. IF= 2.46. https://doi.org/10.1016/j.jgar.2019.04.016
- B. Sloan, H. Mohammad, N. S. Abutaleb & M. N. Seleem. (2019). Comparison between a novel tap water wound irrigation device and a sterile saline device in an animal model. Trauma. 2019-3-1-6. https://doi.org/10.1177/1460408619857399
- M. Elsebaei, N. Abutaleb, Abdulrahman Mahgoub, D. Li, M. Hagras, H. Mohammad, M. N. Seleem & A. Mayhoub. (2019). Phenylthiazoles with Nitrogenous Side Chain: An Approach to Overcome Molecular Obesity. European Journal of Medicinal Chemistry. 19-01362. IF= 4.81. https://doi.org/10.1016/j.ejmech.2019.111593
- X. Shao, A. Abdelkhalek, N. Abutaleb, U. Velagapudi M. N. Seleem & T. Talele. (2019). Chemical space exploration around thieno[3,2-d]pyrimidin-4(3H)-one scaffold led to a novel class of highly active Clostridium difficile inhibitors. Journal of Medicinal Chemistry. 62(21), pp. 9772-9791. IF= 6.25. https://doi.org/10.1021/acs.jmedchem.9b01198
- A. Hammad, N. S. Abutaleb, M. Elsebaei, M. Ali, M. Al-Sawah, M. N. Seleem & A. Mayhoub. (2019). From phenylthiazoles to phenylpyrazoles: Broaden the antibacterial spectrum towards carbapenam-resistant strains. Journal of Medicinal Chemistry. 62(17), pp. 7998-8010 IF= 6.25. https://doi.org/10.1021/acs.jmedchem.9b00720
- N. Dayal, C. Opoku-Temeng, H. Mohammad, N. S. Abutaleb, D. Hernandez, M. N. Seleem & H. Sintim. (2019). Inhibitors of Intracellular Gram-Positive Bacterial Growth Synthesized via Povarov−Doebner Reactions. ACS Infectious Diseases. 5(11), pp. 1820-1830. IF= 4.91. https://doi.org/10.1021/acsinfecdis.9b00022
- S. Al-Trawneh, N. Abutaleb, E. Salama, A. Tarawneh, and M. N. Seleem. (2019). Synthesis of New Pyrazolo Triazines with antifungal antibiofilm activity. Medicinal Chemistry Research. MCRE-D-19-00300 IF= 1.7. https://doi.org/10.1007/s11696-019-00974-9
- D. Mody, A. Athamneh, & M. N. Seleem. (2019). Curcumin: A natural derivative with antibacterial activity against Clostridium difficile. Journal of Global Antimicrobial Resistance. JGAR-D-19-00442. IF= 2.9. https://doi.org/10.1016/j.jgar.2019.10.005
- M. Alhashimi & M. N. Seleem. (2019). Repurposing salicylamide for combating multidrug-resistant Neisseria gonorrhoeae. Antimicrobial Agents and Chemotherapy 63(12),e01225-19. IF= 4.7. https://doi.org/10.1128/AAC.01225-19
- Mohammad, H., Eldesouky, H.E., Hazbun, T., Mayhoub, A.S., M. N. Seleem. (2019). Identification of a Phenylthiazole Small Molecule with Dual Antifungal and Antibiofilm Activity Against Candida albicans and Candida auris. Scientific Reports 9(1),18941 IF= 4.25. https://doi.org/10.1038/s41598-019-55379-1
2018
- M. Hagras, Y. Hegazy, A. Elkabbany, H. Mohammad, A. Ghiaty, T. Abdelgahny & M. N. Seleem & A. Mayhoub. (2018). Biphenylthiazole antibiotics with an oxadiazole linker: An approach to improve physicochemical properties and oral bioavailability. European Journal of Medicinal Chemistry. 143: 1448-1456. IF= 4.81. https://doi.org/10.1016/j.ejmech.2017.10.048
- H. Eldesouky, A. Mayhoub, T. R. Hazbun & M. N. Seleem. (2018). Reversal of azole resistance in Candida albicans by sulfa antibacterial drugs. Antimicrobial Agents and Chemotherapy 62 (3): e00701-17. IF= 4.45. https://doi.org/10.1128/AAC.00701-17
- H. Mohammad, A. Abdelkhalek, N. Abutaleb & M. N. Seleem. (2018). Evaluation of the anthelmintic drug niclosamide for intestinal decolonization of vancomycin-resistant Enterococci. International Journal of Antimicrobial Agents 51 (6): 897-904. IF= 4.30. https://doi.org/10.1016/j.ijantimicag.2018.02.003
- W. Hong, C. W. Karanja, W. Younis, X. Zhang, M. N. Seleem & Ji-Xin Cheng. (2018). Antibiotic susceptibility determination within one cell cycle at single bacterium level by stimulated Raman metabolic imaging. Analytical Chemistry 90(6):3737-3743 IF= 6.32. https://doi.org/10.1021/acs.analchem.7b03382
- H. Mohammad, N. ElGhazawy, H. Eldesouky, Y. Hegazy, W. Younis, L. Avrimova, T. Hazbun, R. Arafa & M. N. Seleem. (2018). Discovery of a novel dibromoquinoline compound exhibiting potent antifungal and antivirulence activity that targets metal ion homeostasis. ACS Infectious Diseases. 4 (3): 403-414 IF= 4.91. https://doi.org/10.1021/acsinfecdis.7b00215
- M. M. Elsebaei, H. Mohammad, M. Abouf, N. Abutaleb, Y. Hegazy, A. Ghiaty, L. Chen, J. Zhang, E. Oldfield, M. N. Seleem & A. Mayhoub.(2018). Alkynyl-containing phenylthiazoles: Systemically active antibacterial agents effective against methicillin-resistant Staphylococcus aureus (MRSA). European Journal of Medicinal Chemistry 148: 195-209. IF= 4.81. https://doi.org/10.1016/j.ejmech.2018.02.031
- B. E. Bergstrom, A. Abdelkhalek, W. Younis, G. K. Hammac, W. M. Townsend & M. N. Seleem. (2018). Antibacterial activity and safety of commercial veterinary cationic steroid antibiotics and neutral superoxidized water. PloS One 13(3):e0193217. IF= 2.8. https://doi.org/10.1371/journal.pone.0193217
- C. Opoku-Temeng, H. Mohammad, N. Dayal, G. Naclerio, N. Abutaleb , M. N. Seleem & H. Sintim. (2018). N-(1,3,4-oxadiazol-2-yl)benzamide analogs, bacteriostatic agents against methicillin- and vancomycin-resistant bacteria. European Journal of Medicinal Chemistry. 155: 797-805. IF= 4.81. https://doi.org/10.1016/j.ejmech.2018.06.023
- A. Kotb, N. Abutaleb, M. Seleem, M. Hagras, H. Mohammad, A. Bayoumi, A. Ghiaty, M. N. Seleem & A. Mayhoub.(2018). Phenylthiazoles with tert-Butyl Side Chain: Metabolically stable with anti-biofilm activity. European Journal of Medicinal Chemistry. 151; 110-120. IF= 4.81 . https://doi.org/10.1016/j.ejmech.2018.03.044
- M. Awamy, H. Mohammad, A. Hussien, N. Abutaleb, M. Hagras, R. Serya, A. Taher, K. Abuzaid, M. N. Seleem & A. Mayhoub.(2018). Alkoxyphenylthiazoles with broad-spectrum activity against multidrug-resistant Gram-positive bacterial pathogens. European Journal of Medicinal Chemistry. 152: 318-328. IF= 4.81. https://doi.org/10.1016/j.ejmech.2018.04.049
- A. Abdelkhalek, N. Abutaleb, K. Elmagarmid & M. N. Seleem. (2018). Repurposing auranofin as an intestinal decolonizing agent for vancomycin-resistant Enterococci. Scientific Reports 8 (1): 8353 IF= 4.25. https://doi.org/10.1038/s41598-018-26674-0
- M. Nepal, M. Mohamed, R. Blade, H. Eldesouky, T. Anderson, M. N. Seleem & J. Chmielewski (2018). A library approach to cationic amphiphilic polyproline helices that target intracellular pathogenic bacteria. ACS Infectious Diseases 4; 1300-1305. IF= 4.91. https://doi.org/10.1021/acsinfecdis.8b00124
- A. Abdelkhalek, N. Abutaleb, H. Mohammad & M. N. Seleem. (2018). Repurposing ebselen for decolonization of vancomycin-resistant enterococci (VRE). PloS One 13 (6): e0199710 IF= 2.8. https://doi.org/10.1371/journal.pone.0199710
- H. Eldesouky, L. Xiaoyan, N. Abutaleb, H. Mohammad & M. N. Seleem. (2018). Synergistic interactions of sulfamethoxazole and azole antifungal drugs against emerging multidrug-resistant Candida auris. International Journal of Antimicrobial Agents. 52 (6): 754-761 IF= 4.30. https://doi.org/10.1016/j.ijantimicag.2018.08.016
- A. Morales, T. Maltais, L. Lu, W. Younis, N. Kadasala, M. N. Seleem & A. Wei. (2018). Rapid uptake and photodynamic inactivation of Staphylococci by ga(III)-protoporphyrin IX. ACS Infectious Diseases 11; 1564-1573. IF= 4.82. https://doi.org/10.1021/acsinfecdis.8b00125
2017
- E. Yahia, H. Mohammad, T. Abdelghany, E. Fayed, M. N. Seleem & A. Mayhoub. (2017). Phenylthiazole antibiotics: A metabolism-guided approach to overcome short duration of action. European Journal of Medicinal Chemistry 126: 604-61. IF= 4.81. https://doi.org/10.1016/j.ejmech.2016.11.042
- S. Thangamani, M. Maland, H. Mohammad, P. Pascuzzi , L. Avramova, C. Koehler, T. Hazbun & M. N. Seleem. (2017). Repurposing approach identifies auranofin with broad spectrum antifungal activity that targets Mia40-Erv1 pathway. Frontiers in Cellular and Infection Microbiology 7:4. IF= 4.3. https://doi.org/10.3389/fcimb.2017.00004
- W. Younis, A. AbdelKhalek, A. Mayhoub & M. N. Seleem. (2017). In vitro screening of an FDA-approved library against ESKAPE pathogens. Current pharmaceutical design 23(14):2147-2157. IF= 3.052. http://doi.org/10.2174/1381612823666170209154745
- C. Ghosh, V. Yadav, W. Younis, H. Mohammad, Y. Hegazy, M.N. Seleem, K. Sanyal & J. Haldar. (2017). Aryl-alkyl-lysines: Membrane-active fungicides that act against biofilms of Candida albicans. ACS Infectious Diseases 3(4):293-301. IF= 4.91. https://doi.org/10.1021/acsinfecdis.6b00192
- I. Eissa, H. Mohammad, O. Qassem, W. Younis, T. Abdelghany, A. Elshafeey, M. Moustafa, M.N. Seleem & A. Mayhoub. (2017). Diphenylurea derivatives for combating methicillin-and vancomycin-resistant Staphylococcus aureus. European Journal of Medicinal Chemistry 130; 73-85. IF= 4.81. https://doi.org/10.1016/j.ejmech.2017.02.044
- H. Mohammad, K. Kyei-Baffourb, W. Younis, D. Davis, H. Eldesouky, M. N. Seleem & M. Dai. (2017). Investigation of aryl isonitrile compounds with potent, broad-spectrum antifungal activity. Bioorganic & Medicinal Chemistry 25:2926–2931. IF= 3.79. https://doi.org/10.1016/j.bmc.2017.03.035
- S. Thangamani, H. Eldesouky, H. Mohammad, P. Pascuzzi, L. Avramova, T. Hazbun & M.N. Seleem. (2017). Ebselen exerts antifungal activity by regulating glutathione (GSH) and reactive oxygen species (ROS) production in fungal cells. Biochimica et Biophysica Acta (BBA)-General Subjects 1861 (1): 3002-3010. IF= 4.70. https://doi.org/10.1016/j.bbagen.2016.09.029
- M. Mohamed, A. Brezden, H. Mohammad, J. Chmielewski & M.N. Seleem. (2017). Targeting biofilms and persisters of ESKAPE pathogens with P14KanS, a kanamycin peptide conjugate. Biochimica et Biophysica Acta (BBA)-General Subjects 1861 (4): 848-859. IF= 4.70. https://doi.org/10.1016/j.bbagen.2017.01.029
- H. Mohammad, W. Younis, L. Chen, C. Peters, J. Pogliano, K. Pogliano, B. Cooper, J. Zhang, A. Mayhoub, E. Oldfield, M. Cushman & M.N. Seleem. (2017). Phenylthiazole antibacterial agents targeting cell wall synthesis exhibit potent activity in vitro and in vivo against vancomycin-resistant enterococci. Journal of Medicinal Chemistry 60(6):2425-2438. IF= 6.25. https://doi.org/10.1021/acs.jmedchem.6b01780
- M. Hagras, H. Mohammad, M. Mandour, Y. Hegzy, A. Ghiaty, M. N. Seleem & A. Mayhoub. (2017). Investigating the antibacterial activity of biphenylthiazoles against methicillin- and vancomycin-resistant Staphylococcus aureus (MRSA and VRSA). Journal of Medicinal Chemistry. 60 (9): 4074–4085. IF= 6.25. https://doi.org/10.1021/acs.jmedchem.7b00392
- X. Yin, H. Mohammed, H. Eldesouky, A. Hassan, M. N. Seleem & M. Dai. (2017). Rapid synthesis of vicyclic lactones via palladium-catalyzed aminocarbonylative lactonizations. Chemical Communications. 53;7238-7241. IF= 6.319. https://doi.org/10.1039/C7CC02494K
- M. Mohamed, A. Brezden, H. Mohammad, J. Chmielewski & M.N. Seleem. (2017). A short D-enantiomeric antimicrobial peptide with potent immunomodulatory and antibiofilm activity against multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii. Scientific Reports 7: 6953. IF= 4.25. https://doi.org/10.1038/s41598-017-07440-0
- H. Hussain, Z. Iqbal, M. N. Seleem, D. Huang, A. Sattar, H. Hao & Z. Yuan. (2017). Virulence and transcriptome profile of multidrug-resistant Escherichia coli from chicken. Scientific Reports. 7: 8335. IF= 4.25. https://doi.org/10.1038/s41598-017-07798-1
- Y. Pei, M. F. Mohamed, M. N. Seleem & Y. Yeo. (2017). Particle engineering for intracellular delivery of vancomycin to methicillin-resistant Staphylococcus aureus (MRSA)-infected macrophages. The Journal of Controlled Release. 267; 133-143. IF= 7.87 . https://doi.org/10.1016/j.jconrel.2017.08.007
- H. Mohammad, W. Younis, H. Ezzat, C. Peters, A. Abdelkhalek, J. Pogliano, K. Pogliano, B. Cooper, A. Mayhoub & M. N. Seleem. (2017). Diphenylurea compounds targeting bacterial cell wall synthesis exhibit potent antibacterial activity. PLoS One. 12(8):e0182821. IF= 2.8. https://doi.org/10.1371/journal.pone.0182821
- M. I. Hamed, T. L. McCalla, W. M. Townsend & M. N. Seleem. (2017). Staphylococcus pseudintermedius Isolated from Two Dog Cases with Ophthalmic Lesions. American Journal of Infectious Diseases and Microbiology, 5(4): 132-136. http://pubs.sciepub.com/ajidm/5/4/2
- C. W. Karanja, W. Hong, W. Younis, H. Eldesouky, M. N. Seleem & Ji-Xin Cheng. (2017). Stimulated Raman imaging reveals aberrant lipogenesis as a metabolic marker for azole-resistant Candida albicans. Analytical Chemistry. 18; 9822-9829. IF= 6.32. https://doi.org/10.1021/acs.analchem.7b01798
- I. Eid, M. Elsebaei, H. Mohammad, M. Hagras, C. E. Peters, Y. Hegazy, B. Cooper, J. Pogliano, K. Pogliano, H. S. Abulkhair, M. N. Seleem & A. Mayhoub. (2017). Arylthiazole Antibiotics Targeting Intracellular Methicillin-resistant Staphylococcus aureus (MRSA) Interfere with Bacterial Cell Wall Synthesis. European Journal of Medicinal Chemistry.139; 665-673. IF= 4.81. https://doi.org/10.1016/j.ejmech.2017.08.039
2016
- M. Abushahba, H. Mohammad, S. Thangamani, A. Hussein & M. N. Seleem. (2016). Impact of different cell penetrating peptides on the efficacy of antisense therapeutics for targeting intracellular pathogens. Scientific Reports 6: 20832. IF= 4.25. https://doi.org/10.1038/srep20832
- S. Thangamani, H. Mohammad, M. Abushahba, T. Sobreira & M. N. Seleem. (2016). Repurposing auranofin for the treatment of cutaneous staphylococcal infections. International journal of antimicrobial agents 47 (3): 195-201. IF= 4.30. https://doi.org/10.1016/j.ijantimicag.2015.12.016
- S. Thangamani, H. Mohammad, M. Abushahba, T. Sobreira, V Hedrick, L. Paul & M. N. Seleem. (2016). Antibacterial activity and mechanism of action of auranofin against multi-drug resistant bacterial pathogens. Scientific Reports 6: 22571. IF= 4.25. https://doi.org/10.1038/srep22571
- W. Hong, C. Liao, H. Zhao, W. Younis, Y. Zhang, M. N. Seleem & J. Cheng. (2016). In situ detection of a single bacterium in complex environment by hyperspectral CARS imaging. ChemistrySelect 3: 513–517 IF 1.505 . https://doi.org/10.1002/slct.201600166
- M. Seleem, A. Disouky, H. Mohammad, T. Abdelghany, A. Mancy, S. Bayoumi, A. Elshafeey, A. El-Morsy, M. N. Seleem & A. S. Mayhoub. (2016). Second-generation phenylthiazole antibiotics with enhanced pharmacokinetic properties. Journal of Medicinal Chemistry 59(10):4900-12. IF= 6.25. https://doi.org/10.1021/acs.jmedchem.6b00233
- M. Abushahba, H. Mohammad & M. N. Seleem (2016). Targeting multidrug-resistant Staphylococci with an anti-rpoA peptide nucleic acid conjugated to the HIV-1 TAT cell penetrating peptide. Molecular Therapy—Nucleic Acids 5 (7): e339. IF= 6.39. https://doi.org/10.1038/mtna.2016.53
- M. Abushahba, A. Hussein, M. N. Seleem & R Hassanein. (2016). Listeria monocytogenes: Overview and Targeting Advances. Journal of Advanced Veterinary Research 6 (2): 72-80. https://advetresearch.com/index.php/AVR/article/view/30/26
- T. Maltais, A. Adak, W. Younis, M. N. Seleem & A. Wei. (2016). Label-Free detection and discrimination of bacterial pathogens based on hemin recognition. Bioconjugate Chemistry 27 (7): 1713–1722. IF= 4.81. https://doi.org/10.1021/acs.bioconjchem.6b00236
- A. AbdelKhalek, C. Ashby, B. Patel, T. Talele & M. N. Seleem. (2016). In vitro antibacterial activity of rhodanine derivatives against pathogenic clinical isolates. PLoS One 11(10):e0164227. IF= 2.8. https://doi.org/10.1371/journal.pone.0164227
- A. Brezden, M. Mohamed, M. Nepal, J. Harwood, J. Kuriakose, M. N. Seleem & J. Chmielewski. (2016). Dual targeting of intracellular pathogenic bacteria with a cleavable conjugate of kanamycin and an antibacterial, cell penetrating peptide. Journal of the American Chemical Society 138 (34): 10945–10949. IF= 14.35. https://doi.org/10.1021/jacs.6b04831
- W. Younis, H. Mohammad, M. Hostetler, D. López-Pérez, C. Steussy, M. Lipton, C. Stauffacher, S. Sultan, M. Wael, A. Hussein & M. N. Seleem . (2016). Class II HMG-CoA reductase inhibitors targeting methicillin-resistant Staphylococcus pseudintermedius. Journal of Advanced Veterinary Research (7)1: 1-6. https://advetresearch.com/index.php/AVR/article/view/3/3
- Z. Iqbal, M. N. Seleem, H. Iftikhar H. Huang, H. Hao & Z. Yuan. (2016). Comparative virulence studies and transcriptome analysis of Staphylococcus aureus strains isolated from animals. Scientific Reports 6: 35442. IF= 4.25. https://doi.org/10.1038/srep35442
- M. Mohamed, A. Abdelkhalek & M. N. Seleem. (2016). Evaluation of short synthetic antimicrobial peptides for treatment of drug-resistant and intracellular Staphylococcus aureus. Scientific Reports 6: 29707. IF= 4.25. https://doi.org/10.1038/srep29707
2015
- S. Thangamani, H. Mohammad, M. Abushahba, M. Hamed, T. Sobreira, V. Hedrick, L. Paul & M. N. Seleem. (2015). Exploring simvastatin, an antihyperlipidemic drug, as a potential topical antibacterial agent. Scientific Reports 5: 16407. IF= 4.25. https://doi.org/10.1038/srep16407
- H. Mohammad, M. Cushman & M. N. Seleem. (2015). Antibacterial evaluation of synthetic thiazole compounds in vitro and in vivo in a methicillin-resistant Staphylococcus aureus (MRSA) Skin Infection Mouse Model. PLoS One 10(11):e0142321. IF= 2.8. https://doi.org/10.1371/journal.pone.0142321
- S. Thangamani, M. Nepal, J. Chmielewsk & M. N. Seleem. (2015). Antibacterial activity and therapeutic efficacy of Fl-PRPRPL-5, a cationic amphiphilic polyproline helix, in a mouse model of staphylococcal skin infection. Drug Design, Development and Therapy 9: 5749—5754. IF= 3.02. https://doi.org/10.2147/DDDT.S94505
- S. Thangamani, W. Younis & M. N. Seleem. (2015). Repurposing celecoxib as a topical antimicrobial agent. Frontiers Microbiology 28: 6:750. IF= 4.16. https://doi.org/10.3389/fmicb.2015.00750
- S. Thangamani, W. Younis & M. N. Seleem. (2015). Repurposing clinical molecule ebselen to combat drug resistant pathogens. PLoS One 10 (7):e0133877. IF= 2.8. https://doi.org/10.1038/srep11596
- W. Younis, S. Thangamani & M. N. Seleem. (2015). Repurposing Non-antimicrobial Drugs and Clinical Molecules to Treat Bacterial Infections. Current Pharmaceutical Design 21(28):4106-11. IF= 3.052. http://doi.org/10.2174/1381612821666150506154434
- Dabral N, Jain-Gupta N, M. N. Seleem, Sriranganathan N & Vemulapalli R. (2015). Overexpression of Brucella putative glycosyltransferase WbkA in Brucella abortus RB51 leads to production of exopolysaccharide. Frontiers in Cellular and Infection Microbiology 24;5:54. IF= 4.3. https://doi.org/10.3389/fcimb.2015.00054
- Davis DC, Mohammad H, Kyei-Baffour K, Younis W, Creemer CN, M. N. Seleem & Dai M. (2015). Discovery and characterization of aryl isonitriles as a new class of compounds versus methicillin- and vancomycin-resistant Staphylococcus aureus. European Journal of Medicinal Chemistry 101:384-390. IF= 4.81. https://doi.org/10.1016/j.ejmech.2015.06.031
- S. Thangamani, W. Younis & M. N. Seleem. (2015). Repurposing ebselen for treatment of multidrug-resistant staphylococcal infections. Scientific Reports 5:11596. IF= 4.25. https://doi.org/10.1038/srep11596
- M. Nepal, S. Thangamani, M. N. Seleem & J. Chmielewski. (2015). Targeting intracellular bacteria with an extended cationic amphiphilic polyproline helix. Organic & Biomolecular Chemistry 13 (21):5930-6. IF= 3.56. https://doi.org/10.1039/C5OB00227C
- H. Mohammad, PV Reddy, D. Montelenoe, AS Mayhoub, M. Cushman, GK Hammac & M. N. Seleem. (2015). Antibacterial Characterization of Novel Synthetic Thiazole compounds against methicillin-resistant Staphylococcus pseudintermedius. PLoS One 10(6):e0130385. IF= 2.8. https://doi.org/10.1371/journal.pone.0130385
- Mohammad, H., Reddy, P.V.N., Monteleone, D., Cushman, M., & M. N. Seleem. (2015). Synthesis and antibacterial evaluation of a novel series of synthetic phenylthiazole compounds against methicillin-resistant Staphylococcus aureus (MRSA). European Journal of Medicinal Chemistry 94:306-316. IF= 4.81. https://doi.org/10.1016/j.ejmech.2015.03.015
- H. Mohammad, S. Thangamani & M. N. Seleem. (2015). Antimicrobial peptides and peptidomimetics-potent therapeutic allies for staphylococcal infections. Current Pharmaceutical Design 21 (16): 2073-2088. IF= 3.052 (invited review article) . http://doi.org/10.2174/1381612821666150310102702
- S. Thangamani, H. Mohammad, W. Younis & M. N. Seleem. (2015). Repurposing non-antimicrobial drugs for treatment of staphylococcal infections. Current Pharmaceutical Design 21 (16): 2089-2100. IF= 3.052 (invited review article). http://doi.org/10.2174/1381612821666150310104416
- H. Mohammad, A. S. Mayhoub, M. Cushman & M. N. Seleem. (2015). Anti-biofilm activity and synergism of novel thiazole compounds with glycopeptide antibiotics against multidrug-resistant staphylococci. Nature Journal of Antibiotics 68(4):259-66. IF= 2.23. https://doi.org/10.1038/ja.2014.142
2014
- E. A. Swanson, L. J. Freeman, M. N. Seleem & P. W. Snyder. (2014). Biofilm-infected wounds in a dog: Case report and review of the literature. Journal of the American Veterinary Medical Association 244(6): 699-707. IF=1.67 . https://doi.org/10.2460/javma.244.6.699
- W. Lv, B. Banerjee, K. Molland, M. N. Seleem, A. Ghafoor, M. Hamed, B. Wan, S. Franzblau & A. Mesecar, M. Cushman. (2014). Synthesis and Antibacterial Activity of 3-(3-Aryl-pyrrolidin-1-yl)-5-aryl-1,2,4-triazine Inorganic Pyrophosphatase Inhibitors. Bioorganic & Medicinal Chemistry 22 (1): 406-18. IF=2.95. https://doi.org/10.1016/j.bmc.2013.11.011
- H. Mohammad, A. S. Mayhoub, A. Ghafor, M. Soofi, R. Alajlouni, M. Cushman & M. N. Seleem. (2014). Discovery and characterization of potent substituted thiazole compounds versus methicillin-and vancomycin-resistant Staphylococcus aureus. Journal of Medicinal Chemistry 57 (4): 1609–1615. IF= 6.25. https://doi.org/10.1021/jm401905m
- A. Athamneh, R. Alajlouni, R. S. Wallace, M. N. Seleem & Ryan Senger. (2014). Phenotypic profiling of antibiotic response signatures in Escherichia coli using Raman spectroscopy. Antimicrobial Agents and Chemotherapy 58 (3): 1302–1314. IF=4.45 . https://doi.org/10.1128/AAC.02098-13
- M. F. Mohamed, M. I. Hamed, A. Panitch & M. N. Seleem. (2014).Targeting methicillin-resistant Staphylococcus aureus with short synthetic peptides: coupling membrane disruption with DNA binding. Antimicrobial Agents and Chemotherapy 58 (7): 4113-4122. IF= 4.45 . https://doi.org/10.1128/AAC.02578-14
- M. F. Mohamed & M. N. Seleem. (2014). Efficacy of short novel antimicrobial and anti-inflammatory peptides in a mouse model of methicillin-resistant Staphylococcus aureus (MRSA) skin infection. Drug Design, Development and Therapy 8: 1979-1983. IF= 3.02. https://doi.org/10.2147/DDDT.S72129
- M. F. Mohamed, G. K. Hammac, L. Guptill & M. N. Seleem. (2014). Antibacterial activity of novel cationic peptides against clinical isolates of multi-drug resistant staphylococcus pseudintermedius from infected dogs. PLoS One 9(12):e116259. IF= 2.80. https://doi.org/10.1371/journal.pone.0116259
2011-2013
- N. Jain, A. Contreras, G. Kimswade, M. N. Seleem, S. M. Boyle & N. Sriranganathan. (2011). Effect of entF deletion on iron acquisition and erythritol metabolism by Brucella abortus 2308. FEMS Microbiology Letters 316 (1):1-6. IF= 2.72. https://doi.org/10.1111/j.1574-6968.2010.02186.x
- P. Rajasekaran, N. Surendran, M. N. Seleem, N. Sriranganathan, G. G. Schurig & S. M. Boyle. (2011). Over-expression of homologous antigens in a leucine auxotroph of Brucella abortus strain RB51 protects mice against a virulent Brucella suis challenge. Vaccine 29 (17):3106-3110. IF= 3.48. https://doi.org/10.1016/j.vaccine.2011.02.054
- A. Ranjan, N. Pothayee, M. N. Seleem, S. M. Boyle, R. Kasimanickam, J. S. Riffle &N. Sriranganathan . (2012). Nanomedicine for intracellular therapy. FEMS Microbiology letters 332 (1):1-9. IF=2.72. https://doi.org/10.1111/j.1574-6968.2012.02566.x
- M. Soofi & M. N. Seleem. (2012). Targeting Salmonella essential genes with antisense peptide nucleic acid. Antimicrobial Agents and Chemotherapy 56 (12): 6407-9. IF= 4.45 . https://doi.org/10.1128/AAC.01437-12
- P. Rajesekaran, J. Alexander, M. N. Seleem, N. Jain, N. Sriranganathan, A. Wattam, J. Setubal & S. M. Boyle. (2013). Peptide nucleic acids inhibit Brucella suis in pure culture and infected macrophages. International Journal of Antimicrobial Agents 41 (4): 358-62. IF= 4.3. https://doi.org/10.1016/j.ijantimicag.2012.11.017
- R. Alajlouni & M. N. Seleem. (2013). Targeting Listeria monocytogenes rpoA and rpoD genes using peptide nucleic acid. Nucleic Acid Therapeutics 23(5): 363-7. IF=2.88. https://doi.org/10.1089/nat.2013.0426
- J. Kuriakose, V. Hernandez-Gordillo, M. Nepal, A.a Brezden, V. Pozzi, M. N. Seleem, & J. Chmielewski. (2013). Targeting intracellular pathogenic bacteria with unnatural proline-rich peptides: coupling antibacterial activity with macrophage penetration. Angewandte Chemie International Edition 52(37):9664-7. IF=12.1. https://doi.org/10.1002/anie.201302693
2004-2010
- M. N. Seleem, R. Vemulapalli, S. M. Boyle, G. G. Schurig & N. Sriranganathan. (2004). Improved expression vector for Brucella species. BioTechniques 37 (5): 740-744. IF= 2.75. https://doi.org/10.2144/04375BM05
- A. Bandara, M. N. Seleem, C. Jordan, D. Lindsay, G. G. Schurig, & N. Sriranganathan. (2006). Brucella abortus strain RB51 can be used to express potentially protective antigens of Toxoplasma gondii. Journal of eukaryotic microbiology 53 (S1): S166–S168. IF= 2.91. https://doi.org/10.1111/j.1550-7408.2006.00218.x
- A. Contreras, M. N. Seleem, S. M. Boyle, G. G. Schurig, N. Sriranganathan & A. Lopez-merino. (2006). Cloning, expression and characterization of immunogenic aminopeptidase N from Brucella melitensis. FEMS Immunology and Medical Microbiology 48 (2): 252-256. IF= 3.07. https://doi.org/10.1111/j.1574-695X.2006.00145.x
- M. N. Seleem, M. Ali, S. M. Boyle, B. Mukhopadhyay, S. G. Witonsky, G. G. Schurig & N. Sriranganathan. (2006). Establishment of gene expression system in Ochrobactrum anthropi. Applied and Environmental Microbiology 72 (10): 6833-6836. IF= 3.95 . https://doi.org/10.1128/AEM.01446-06
- M. N. Seleem, M. Ali, M. Abd Alazim, S. M. Boyle & N. Sriranganathan. (2007). High-level heterologous gene expression in Ochrobactrum anthropi using an A-rich UP element. Applied Microbiology and Biotechnology 73 (5):1123-1127. IF=3.81. https://doi.org/10.1007/s00253-006-0555-7
- M. N. Seleem, M. Ali, M. Abd Alazim, S. M. Boyle & N. Sriranganathan. (2007). Enhanced expression, detection and purification of recombinant protein using tandem fusion tags RNA stem loop. Applied Microbiology and Biotechnology 75 (6):1385-1392. IF=3.81. https://doi.org/10.1007/s00253-007-0970-4
- M. N. Seleem, S. M. Boyle & N. Sriranganathan. (2008). Brucella; a pathogen without classical virulence genes. Veterinary Microbiology 129 (1-2):1-14. IF=2.72. https://doi.org/10.1016/j.vetmic.2007.11.023
- M. N. Seleem, P. Rajasekaran, M. Ali, S. M. Boyle & N. Sriranganathan. (2008). Simple Method for Transformation of Ochrobactrum anthropi. World Journal of Microbiology and Biotechnology 24 (10): 2111-2114. IF=2.10. https://doi.org/10.1007/s11274-008-9716-4
- I. Sandal, M. N. Seleem, Elswaifi, N. Sriranganathan & T. Inzana. (2008). Construction of a high-efficiency shuttle vector for Histophilus somni. Journal of Microbiological Methods 74 (2-3):106-109. IF=2.09. https://doi.org/10.1016/j.mimet.2008.04.002
- M. N. Seleem, M. Ali, S.M. Boyle & N. Sriranganathan. (2008). Vectors for enhanced gene expression and protein purification in Salmonella. Gene 421 (1-2): 95-98. IF=2.49. https://doi.org/10.1016/j.gene.2008.06.021
- N. Pothayee, M. L. Vadala, A. Ranjan, N. Jain, M. N. Seleem, N. Sriranganathan & J. S. Riffle. (2008). Aminoglycoside-Ionopolymeric nanoplexes for targeting intracellular bacterial pathogens. Polymer Preprints 49 (2): 1036-1037. IF not determined. https://doi.org/10.1128/AAC.45.11.2977-2986.2001
- M. N. Seleem, M. Ali, S. M. Boyle & N. Sriranganathan. (2008). Reporter genes for real-time in vivo monitoring of Ochrobactrum anthropi infection. FEMS Microbiology letters 286 (1):124-129. IF= 2.72. https://doi.org/10.1111/j.1574-6968.2008.01270.x
- P. Rajasekaran, M. N. Seleem, A. Contreras, N. Sriranganathan & S. Boyle. (2008). A leucine auxotroph of Brucella abortus strain RB51 vaccine as an environmentally safe vector for plasmid maintenance and antigen expression. Applied and Environmental Microbiology 74 (22): 7051-7055. IF= 3.95 . https://doi.org/10.1128/AEM.01511-08
- M. N. Seleem, N. Jain, H. Alqublan, R. Vemulapalli, S. M. Boyle, & N. Sriranganathan. (2008). Activity of native vs. synthetic promoters in Brucella. FEMS Microbiology Letters 288 (2): 211-215. IF= 2.72. https://doi.org/10.1111/j.1574-6968.2008.01358.x
- P. Munusamy, M. N. Seleem, H. Alqublan, R. Tyler, N. Sriranganathan & G. Pickrell. (2009). Targeted drug delivery using silica xerogel systems to treat diseases due to intracellular pathogens. Material Science and Engineering C 29 (8): 2313-2318. IF=5.08. https://doi.org/10.1016/j.msec.2009.05.020
- M. N. Seleem, Jain N., N. Pothayee., Ranjan A, J. Riffle & N. Sriranganathan. (2009). Targeting Brucella melitensis with polymeric nanoparticles containing streptomycin and doxycycline. FEMS Microbiology Letters 294 (1): 24-31. IF= 2.72. https://doi.org/10.1111/j.1574-6968.2009.01530.x
- A. Ranjan, N. Pothayee, M. N. Seleem, R. Tyler, N. Sriranganathan, R. Kasimanickam, M. Makris & J. S. Riffle. (2009). Antibacterial efficacy of core-shell nanostructures encapsulating gentamicin against in vivointracellular Salmonella model. International Journal of Nanomedicine(4): 289-297. IF=4.37. https://doi.org/10.2147/IJN.S7137
- P. Munusamy, M. N. Seleem, N. Sriranganathan & G. Pickrell. (2009). Synthesis and characterization of Magnetic Silica Xerogels for Targeting Intracellular Pathogens. Journal of Bionanoscience3 (1):16–21. IF not determined. https://doi.org/10.1166/jbns.2009.1004
- A. Ranjan, N. Pothayee, M. N. Seleem, N. Sriranganathan, R. Kasimanickam, M. Makris & J. S. Riffle. (2009). In-vitro trafficking and efficacy of core-shell nanostructures for treating intracellular Salmonella. Antimicrobial Agents and Chemotherapy 53 (9): 3985-3988. IF= 4.45 . https://doi.org/10.1128/AAC.00009-09
- D. Gillaspie, I. Perkins, K. Larsen, A. McCord, S. Pangonis, D. Sweger, M. N. Seleem, N. Sriranganathan, & B. Anderson. (2009). Plasmid based system for high-level gene expression and antisense gene knockdown in Bartonella. Applied and Environmental Microbiology75 (16):5434-5436. IF=3.95 . https://doi.org/10.1128/AEM.00949-09
- M. N. Seleem, P. Munusamy, A. Ranjan, H. Alqublan, G. Pickrell & N. Sriranganathan. (2009). Silica-antibiotic hybrid nanoparticles for targeting intracellular pathogens. Antimicrobial Agents and Chemotherapy 53 (10):4270-4274. IF= 4.45 . https://doi.org/10.1128/AAC.00815-09
- M. N. Seleem, S. M. Boyle & N. Sriranganathan. (2010). Brucellosis; A re-emerging zoonosis. Veterinary Microbiology 140 (3-4):392-398. IF=2.72 (Invited Review Article). The above manuscript is one of the most cited and most downloaded articles in Veterinary Microbiology since 2008. (1049 citations). https://doi.org/10.1016/j.vetmic.2009.06.021
- H. Alqublan, M. N. Seleem, S. M. Boyle, & N. Sriranganathan. (2010). Tightly regulated expression system for Ochrobactrum. Current Microbiology 60 (4):242-247. IF = 1.37. https://doi.org/10.1007/s00284-009-9532-6
- 16. A. Ranjan, N. Pothayee, M. N. Seleem, N. Jain, N. Sriranganathan, J. S. Riffle & R. Ksimanickam. (2010). Drug delivery using novel nanoplexes against a Salmonellamouse infection model. Journal of Nanoparticle Research 12 (3):905–914. IF = 2.27. https://doi.org/10.1007/s11051-009-9641-y
- A. Ranjan, N. Pothayee, T. P. Vadala, M. N. Seleem, E. Restis, N. Sriranganathan, J. S. Riffle & R. Kasimanickam. (2010). Efficacy of amphiphilic Development of pluronic P85 based core-shell nanostructures encapsulating gentamicin against an in-vitro Salmonella and Listeria intracellular infection model. Antimicrobial Agents and Chemotherapy 54 (8):3524-3526. IF= 4.45 . https://doi.org/10.1128/AAC.01522-09
- N. Surendran, K. Zimmerman , M. N. Seleem, N. Sriranganathan, S. M. Boyle, E. M. Hiltbold, H. Lawler, B. Heid & S. Witonsky. (2010). Ability of Brucella abortus rough vaccine strains to elicit DC and innate immunity in lung using a murine respiratory model. Vaccine 28 (43):7009-7015. IF= 3.48. https://doi.org/10.1016/j.vaccine.2010.08.039https://doi.org/10.1111/j.1574-6968.2008.01358.x