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Publication

2025

  

222. M. Zhang, Y. Zhan, H. Lin, J. Chen, M. N. Seleem, M. Mansour, J.-X. Cheng. (2025). SIP‐SRS imaging of cell wall synthesis identifies a synergy between micafungin and amphotericin B. Advanced Science, 2025, e07331. https://doi.org/10.1002/advs.202507331 


221. Y. Elgammal, E. A. Salama, M. N. Seleem. (2025). HIV protease inhibitors restore amphotericin B activity against Candida. PLOS ONE, 2025, 20, 5, e0324080. https://doi.org/10.1371/journal.pone.0324080


220. A. S. Abdelsattar, N. S. Abutaleb, M. N. Seleem. (2025). A novel peptide mimetic, brilacidin, for combating multidrug-resistant Neisseria gonorrhoeae. PLOS ONE, 2025, 20, 6, e0325722. https://doi.org/10.1371/journal.pone.0325722


219. A. Ammara, S. Giovannuzzi, A. Bonardi, N. S. Abutaleb, A. A. Abouelkhair, D. P. Flaherty, M. N. Seleem, C. Capasso, P. Gratteri, A. Nocentini, C. T. Supuran. (2025). Redesigning oxazolidinones as carbonic anhydrase inhibitors against vancomycin-resistant enterococci. European Journal of Medicinal Chemistry, 2025, 291, 117620. https://doi.org/10.1016/j.ejmech.2025.117620


218. K. J. Holly, P. R. Tharra, N. S. Abutaleb, A. Nocentini, A. A. Abouelkhair, M. S. Youse, A. K. Marapaka, A. S. Abdelsattar, W. An, F. L. Drummond, O. C. Snell, C. T. Supuran, M. N. Seleem, D. P. Flaherty. (2025). Hit-to-lead optimization of acetazolamide-based bacterial carbonic anhydrase inhibitors with efficacy in vivo for treatment of vancomycin-resistant enterococci septicemia. Journal of Medicinal Chemistry, 2025, 68, 17, 18597–18624. https://doi.org/10.1016/j.ejmech.2025.117620


217. M.-A. W. Shalaby, N. S. Abutaleb, E. M. E. Dokla, Y. Elgammal, H.-W. Liang, R. A. T. Serya, I. A. Abdallah, J. Fishovitz, M. N. Seleem, K. A. M. Abouzid. (2025). Tackling microbial resistance with 4H-chromen-4-one derivatives as a novel class of penicillin-binding protein 2a inhibitors. Bioorganic & Medicinal Chemistry, 2025, 118376. https://doi.org/10.1016/j.bmc.2025.118376 


216. G. A. Naclerio, C. S. Vennard, K. I. Onyedibe, D. da S. Vieira, N. S. Abutaleb, M. L. Figueiredo, M. N. Seleem, H. O. Sintim. (2025). Halogenated N-(1,3,4-oxadiazol-2-yl) benzamides are effective eradicators of methicillin-resistant Staphylococcus aureus biofilms. Bioorganic & Medicinal Chemistry, 2025, 118437.  https://doi.org/10.1016/j.bmc.2025.118437 


215. M. A. Seleem, N. S. Abutaleb, H. T. Hussein, A. A. Abouelkhair, K. M. P. de Oliveira, F. G. da Silva Dantas, L. J. de Campos, C. Drobotka, F. Aguiar-Alves, M. N. Seleem, M. Conda-Sheridan. (2025). Synthesis, antimicrobial activity, and preliminary mechanistic studies of phenazine sulfonamides. Bioorganic & Medicinal Chemistry, 2025, 118438.  https://doi.org/10.1016/j.bmc.2025.118438 


214. A. A. Abouelkhair, N. S. Abutaleb, M. N. Seleem. (2025). The antiarrhythmic drugs dronedarone and amiodarone exhibit potent in vitro and in vivo activity against Clostridioides difficile. International Journal of Antimicrobial Agents, 2025, 107649.  https://doi.org/10.1016/j.ijantimicag.2025.107649 

2024

213. M. S. Youse, N. S. Abutaleb, A. Nocentini, A. S. Abdelsattar, F. Ali, C. T. Supuran, M. N. Seleem, D. P. Flaherty. Optimization of Ethoxzolamide Analogs with Improved Pharmacokinetic Properties for In Vivo Efficacy against Neisseria gonorrhea. Journal of Medicinal Chemistry, 2024.  https://doi.org/10.1021/acs.jmedchem.4c01187 


212.  Alkashef, N.M. and Seleem, M.N., 2024. Novel combinatorial approach: Harnessing HIV protease inhibitors to enhance amphotericin B’s antifungal efficacy in cryptococcosis. PloS one, 19(8), p.e0308216. https://doi.org/10.1371/journal.pone.0308216


211. A. Abouelkhair and M. N. Seleem. (2024). Exploring Novel Microbial Metabolites and Drugs for Inhibiting Clostridioides difficile. mSphere. https://doi.org/10.1128/msphere.00273-24


210. B. Alessandro, N. Alessio, S. Giovannuzzi, N. Paoletti, A. Ammara, S. Bua, N. Abutaleb, A. S. Abdelsattar, C. Capasso, P. Gratteri, D. Flaherty, M. N. Seleem; C. Supuran. (2024). Development of penicillin-based carbonic anhydrase inhibitors targeting multidrug-resistant Neisseria gonorrhoeae: Journal of Medicinal Chemistry, 2024, 67, 11, 9613–9627. https://doi.org/10.1021/acs.jmedchem.4c00740 


209. S. Sedaghat, A. Krishnakumar, V. Selvamani, J. Barnard, S. Nejati, H. Wang, D. Detwiler, M. N. Seleem, R. Rahimi. (2024). Laser-Assisted Surface Alloying of Titanium with Silver to Enhance Antibacterial and Bone-Cell Mineralization Properties of Orthopedic Implants. Journal of Materials Chemistry B - 2024 May 8;12(18):4489-4501.  DOI: 10.1039/d3tb02481d


208. E. A Salama, Y. Elgammal, A. Wijeratne, N. A Lanman, S. M. Utturkar, A. Farhangian, J. Li, B. Meunier, T. R Hazbun*, M. N. Seleem*. (2024). Lansoprazole interferes with fungal respiration and acts synergistically with amphotericin B against multidrug-resistant Candida auris. Emerging Microbes & Infections. 2322649. https://doi.org/10.1080/22221751.2024.2322649.


207. M. Zhang, H. Ni, X. Ge, L. Lan, M. Seleem, M. Wagner, J. Cheng. (2024). Rapid identification and antimicrobial susceptibility testing in urinary tract infection by FISH-SRS. Advanced Chemical Microscopy for Life Science and Translational Medicine 2024, PC128550F. https://doi.org/10.1117/12.3003454


206. Elgammal, Y., Salama, E.A. and Seleem, M.N., 2024. Enhanced antifungal activity of posaconazole against Candida auris by HIV protease inhibitors, atazanavir, and saquinavir. Scientific Reports, 14(1), p.1571. https://doi.org/10.1038/s41598-024-52012-8


205. Hagras, M., Abuelkhir, A.A., Abutaleb, N.S., Helal, A.M., Fawzy, I.M., Hegazy, M., Seleem, M.N. and Mayhoub, A.S., 2024. Novel phenylthiazoles with a tert-butyl moiety: promising antimicrobial activity against multidrug-resistant pathogens with enhanced ADME properties. RSC advances, 14(2), pp.1513-1526. https://doi.org/10.1039/D3RA07619A

2023

204. Giovannuzzi, S., Marapaka, A. K., Abutaleb, N. S., Carta, F., Liang, H. W., Nocentini, Pisano, L., Seleem, M.N., Flaherty, D.P. and Supuran, C.T. (2023). Inhibition of pathogenic bacterial carbonic anhydrases by monothiocarbamates. Journal of Enzyme Inhibition and Medicinal Chemistry, 38(1), 2284119. https://doi.org/10.1080/14756366.2023.2284119


203. B. Kikiowo, A. B. Bandara, N. S. Abutaleb, M. N. Seleem. (2023). Colonization efficiency of multidrug-resistant Neisseria gonorrhoeae in a female mouse model. Pathogens and Disease, ftad030, https://doi.org/10.1093/femspd/ftad030 (October 2023). 


202. Pal, R., & Seleem, M. N. (2023). Antisense inhibition of RNA polymerase α subunit of Clostridioides difficile. Microbiology Spectrum, e01755-23.  https://doi.org/10.1128/spectrum.01755-23


201.  M. Hagras, N. S. Abutaleb, H. G. Ezzat, E. A. Salama, M. N. Seleem and Abdelrahman S. Mayhoub. (2023). Naphthylthiazoles:Broad Spectrum Class of Antifungals. RSC Med. Chem., 2023. https://doi.org/10.1039/D3MD00323J


200. H. Almolhim, A. Elhassanny, N. Abutaleb, A. S. Abdelsattar, M. N. Seleem, P. Carlier. (2023). Substituted salicylic acid analogs offer improved potency against multidrug-resistant Neisseria gonorrhoeae and good selectivity against commensal vaginal bacteria. Scientific Reports volume 13, Article number: 14468 (2023). https://doi.org/10.1038/s41598-023-41442-5


199. R. A. Wagdy, N. S. Abutaleb, R. K. Fathalla, Y. Elgammal, S. Weck, R. Pal, P. D. Fischer, C. Ducho, A. Abadi, M. N. Seleem, M. Engel, M. Abdel-Halim. (2023). Discovery of 1,2-diaryl-3-oxopyrazolidin-4-carboxamides as a new class of MurA enzyme inhibitors and characterization of their antibacterial activity. European Journal of Medicinal Chemistry. 2023, 115789. https://doi.org/10.1016/j.ejmech.2023.115789


198.  Y. Elgammal, E. Salama, M. N.  Seleem. (2023). Saquinavir potentiates itraconazole's antifungal activity against multidrug-resistant Candida auris in vitro and in vivo. Medical Mycology. myad081. https://doi.org/10.1093/mmy/myad081


197.  M. Omara, M. Hagras, M. M. Elsebaie, N. S. Abutaleb, H. T. Nour El-Din, M. O. Mekhail, A. S. Attia, M. N. Seleem, M. T. Sarg, A. S. Mayhoub. (2023). Exploring novel aryl/heteroaryl-isosteres of phenylthiazole against multidrug-resistant bacteria. RSC Adv, 2023 Jun 29; 13(29): 19695–19709. https://doi.org/10.1039/D3RA02778C


196.  E. A. Salama, H. E. Eldesouky, Y. Elgammal, N. S. Abutaleb, M. N. Seleem. (2023). Lopinavir and ritonavir act synergistically with azoles against Candida auris in vitro and in a mouse model of disseminated candidiasis. International Journal of Antimicrobial Agents, 106906. https://doi.org/10.1016/j.ijantimicag.2023.106906


195. M. Zhang, P.Dong, H. Eldesouky, Y. Zhan, H. Lin, Z. Wang, E. Salama, S. Jusurf, C. Zong, Z.
Chen, M. N. Seleem, J. Cheng. (2023). Fingerprint SRS Imaging Unveils Ergosteryl Ester as a
Metabolic Signature of Azole-Resistant Candida albicans. Analytical Chemistry. June 13, 2023
ac-2023-00900u https://doi.org/10.1021/acs.analchem.3c00900 


194. A. Roth, A. Krishnakumar, R. McCain, K. Maruthamuthu, M. McIntosh, Y. Chen, A. Cox, J. Hopf, N. Amber, M. N. Seleem, R. Rahimi. (2023).  Biocompatibility and Safety Assessment of Combined Topical Ozone and Antibiotics for Treatment of Infected Wounds. ACS Biomaterials Science & Engineering. https://pubs.acs.org/doi/10.1021/acsbiomaterials.2c01548

 

193.  D. Liu; X. Bai, H. Helmick, M. Samaddar, M. Amalaradjou, X. Li, S. Tenguria, N. Gallina, L. Xu, R. Drolia, U. Aryal, G. Moreira, M. Hust, M.N. Seleem, J. Kokini, R. Ostafe, A. Cox, A. K. Bhunia. (2023). Cell Surface Anchoring of Listeria Adhesion Protein on L. monocytogenes is Fastened by Internalin B for Pathogenesis. Cell Reports. 42(5):112515. https://doi.org/10.1016/j.celrep.2023.112515


192. Elgammal, Y., Salama, E. A., & Seleem, M. N. (2023). Atazanavir Resensitizes Candida auris to Azoles. Antimicrobial Agents and Chemotherapy, e01631-22. https://doi.org/10.1128/aac.01631-22 


191.  NS Abutaleb, A Shrinidhi, AB Bandara, M. N Seleem, DP Flaherty (2023). Evaluation of 1, 3, 4-Thiadiazole Carbonic Anhydrase Inhibitors for Gut Decolonization of Vancomycin-Resistant Enterococci. ACS Medicinal Chemistry Letters. March 21, 2023. https://doi.org/10.1021/acsmedchemlett.3c00032


190. HTN El-Din, MM Elsebaie, NS Abutaleb, AM Kotb, AS Attia, M. N. Seleem, A. Mayhoub. (2023). Expanding the structure–activity relationships of alkynyl diphenylurea scaffold as promising antibacterial agents. RSC Medicinal Chemistry 14 (2), 367-377. https://doi.org/10.1039/D2MD00351A


189. S. Bose, C. N. Steussy, D. López-Pérez, T. Schmidt, S. C. Kulathunga, M. N. Seleem, M. Lipton, A. D. Mesecar, V. W. Rodwell & C. V. Stauffacher. (2023). Targeting Enterococcus faecalis HMG-CoA reductase with a non-statin inhibitor. Nature Communications biology 6, Article number: 360 (2023). https://doi.org/10.1038/s42003-023-04639-y


188.  E. M.E. Dokla, N. S. Abutaleb, S. N. Milik, E. Kindil, O. Assem, Y. Elgammal, M. Nasr, M. McPhillie, K. Abouzid, M N. Seleem, P.  Imming, and M. Adel.  (2023). SAR investigation and optimization of benzimidazole-based derivatives as antimicrobial agents against Gram-negative bacteria. European Journal of Medicinal Chemistry. Volume 247, 5 February 2023, 115040. https://doi.org/10.1016/j.ejmech.2022.115040


187.  A. Marapaka, A. Nocentini, M. S. Youse, W. An, K. J. Holly, C. Das, R. Yadav, M. N. Seleem, C. T. Supuran, and D. P. Flaherty. (2023). Structural Characterization of Thiadiazolesulfonamide Inhibitors Bound to Neisseria gonorrhoeae α-Carbonic Anhydrase. ACS Med. Chem. Lett. 2023, 14, 1, 103-109. https://doi.org/10.1021/acsmedchemlett.2c00471


186.  A. M. Sayed, N. S. Abutaleb, A. Kotb, H. G. Ezzat, M. N. Seleem, A. S. Mayhoub, M. M. Elsebaie. (2023). Arylpyrazole as selective anti-enterococci; synthesis and biological evaluation of novel derivatives for their antimicrobial efficacy. J Heterocyclic Chem.2023;60:134–144. https://doi.org/10.1002/jhet.4570

2022

185. Pal R, Seleem MN (2022) Discovery of a novel natural product inhibitor of Clostridioides difficile with potent activity in vitro and in vivo. PLoS ONE 17(8): e0267859. https://doi.org/10.1371/journal.pone.0267859


184. C. W. Karanja, N. Naganna, N. S. Abutaleb, N. Dayal, K. Onyedibe, U. Aryal, M. N. Seleem and H. O. Sintim. (2022). Isoquinoline Antimicrobial Agent: Activity against Intracellular Bacteria and Effect on Global Bacterial Proteome. Molecules 2022, 27(16), 5085; https://doi.org/10.3390/molecules27165085 


183. Roth, M. Maruthamuthu, S. Nejati, A. Krishnakumar, V. Selvamani, S. Sedaghat, J. Nguyen, M. N. Seleem & R. Rahimi. (2022). Wearable adjunct ozone and antibiotic therapy system for treatment of Gram-negative dermal bacterial infection. Scientific Reports, 12: 13927 (2022). https://doi.org/10.1038/s41598-022-17495-3


182. W. An, K. J Holly, A. Nocentini, R. Imhoff, C. Hewitt, N. S. Abutaleb, X. Cao, M. N. Seleem, C. T. Supuran, D.  P.  Flaherty. (2022). Structure-activity relationship studies for inhibitors for vancomycin-resistant Enterococcus and human carbonic anhydrases. Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 1838-1844. https://doi.org/10.1080/14756366.2022.2092729 


181. M. Elsebaie, H. Nour Din, N. S. Abutaleb, A. Abuelkhir, H. Liang, A. Attia, M N Seleem and A.  Mayhoub. (2022). Exploring the Structure-Activity Relationships of Diphenylurea as an Antibacterial Scaffold Active against Methicillin- and Vancomycin-Resistant Staphylococcus aureus. Eur J Med Chem 2022, EJMECH-D-21-03184.  https://doi.org/10.1016/j.ejmech.2022.114204


180. R. Pal, A. Athamneh, R. Deshpande, J. Ramirez, K. Adu, P. Muthuirulan, S. Pawar, M. Biazzo, Y. Apidianakis, U. Sundekilde, C. Fuente-Nunez, M. Martens, G. Tegos, M N Seleem. (2022). Probiotics: insights and new opportunities for Clostridioides difficile intervention. Critical Reviews in Microbiology. 2022.2072705.  https://doi.org/10.1080/1040841X.2022.2072705


179. H. Oliveira, R. Castelli, L. Alves, J. Nosanchuk, E. Salama, M N. Seleem, M. Rodrigues. (2022). Identification of 4 compounds from the Pharmakon library with antifungal activity against Candida auris and species of Cryptococcus. Medical Mycology. myac033. https://doi.org/10.1093/mmy/myac033   


178. G. Naclerio, N. Abutaleb, K. Onyedibe, C. Karanja, H. Eldesouky, H. Liang, A. Dieterly, U. Aryal, T. Lyle, M. N. Seleem, H. O Sintim. 2022. Mechanistic Studies and In Vivo Efficacy of an Oxadiazole-Containing Antibiotic . Journal of Medicinal Chemistry. 2022, 65, 9, 6612–6630. https://doi.org/10.1021/acs.jmedchem.1c02034      


177. AEM Elhassanny, NS Abutaleb, MN Seleem. (2022).  Auranofin exerts antibacterial activity against Neisseria gonorrhoeae in a female mouse model of genital tract infection.  Plos one 17 (4), e0266764. https://doi.org/10.1371/journal.pone.0266764


176. M Zhang, M.N. Seleem, JX Cheng. (2022). Rapid Antimicrobial Susceptibility Testing by Stimulated Raman Scattering Imaging of Deuterium Incorporation in a Single Bacterium. JoVE (Journal of Visualized Experiments), e62398. http://doi.org/10.3791/62398


175. S. Giovannuzzi, N. S. Abutaleb, C. S. Hewitt, F. Carta, A. Nocentini, M N Seleem, D. Flaherty, C. T Supuran. (2022). Dithiocarbamates effectively inhibit the α-carbonic anhydrase from Neisseria gonorrhoeae. Journal of Enzyme Inhibition and Medicinal Chemistry. 2022, VOL. 37, NO. 1, 1-8.   https://doi.org/10.1080/14756366.2021.1988945


174. N. S. Abutaleb, A. Elhassanny, A. Nocentini, C. Hewitt, A. Elkashif, B. Cooper, C. T Supuran, M N Seleem, D. Flaherty. (2022). Repurposing FDA-approved sulphonamide carbonic anhydrase inhibitors for treatment of Neisseria gonorrhoeae. Journal of Enzyme Inhibition and Medicinal Chemistry. 2022, VOL. 37, NO. 1, 51-61.   https://doi.org/10.1080/14756366.2021.1991336


173. N. S. Abutaleb, A. Elhassanny, M N Seleem. (2022). In vivo efficacy of acetazolamide in a mouse model of Neisseria gonorrhoeae infection. 2022.105454. https://doi.org/10.1016/j.micpath.2022.105454

2021

172. M. Hagras, N. S. Abutaleb, A. M Sayed, E. A. Salama, M N Seleem, A.  Mayhoub. (2021). Evaluation of bisphenylthiazoles as a promising class for combating multidrug-resistant fungal infections. Plos one e0258465.  https://doi.org/10.1371/journal.pone.0258465


171. Z. Iqbal, H. Hussain, M N Seleem, M. Shabbir, A. Sattar, A.Aqib, X. Kuang, A. Ihsan, H. Hao. (2021). RNA-seq-based transcriptome analysis of a cefquinome-treated, highly resistant, and virulent MRSA strain. Microbial Pathogenesis. 2021 Nov;160:105201. https://doi.org/10.1016/j.micpath.2021.105201


170. H. Mohammad, N. S. Abutaleb, A. M. Dieterly, L. T. Lyle & M. N. Seleem. (2021). Investigating auranofin for the treatment of infected diabetic pressure ulcers in mice and dermal toxicity in pigs. Scientific Reports 11, 10935 (2021). https://doi.org/10.1038/s41598-021-90360-x


169. M. Hamed and M. N. Seleem. (2021). Evaluation of Short Synthetic Antimicrobial Peptides against Staphylococcus pseudintermedius. Journal of Advanced Veterinary Research 11,2,(2021) 69-72. https://advetresearch.com/index.php/AVR/article/view/652/459


168. R. Pal, M. Dai, & M. N. Seleem. (2021). High-throughput screening identifies a novel natural product-inspired scaffold capable of inhibiting Clostridioides difficile in vitro. Scientific Reports 11, 10913 (2021). https://doi.org/10.1038/s41598-021-90314-3


167. H. Hussain, A. Aqib, M.N. Seleem , M. Shabbir, H. Hao, Z. Iqbal, M. Kulyar, T. Zaheer , K. Li. (2021). Genetic basis of molecular mechanisms in β-lactam resistant gram-negative bacteria. Jun10;158:105040. Micro. Patho. 158, 2021, 105040. https://doi.org/10.1016/j.micpath.2021.105040


166. Woodhouse, S. Nejati, V. Selvamani, H. Jiang, S. Chittiboyina, J. Grant, Z. Mutlu, J. Waimin, N. S. Abutaleb, M. N. Seleem, R. Rahimi (2021). Flexible Microneedle Array Patch for Chronic Wound Oxygenation and Biofilm Eradication ACS Appl. Bio Mater. 2021, 4, 7, 5405–5415. https://doi.org/10.1021/acsabm.1c00087


165. S. A Yuk, H. Kim, N. S. Abutaleb, A. M. Dieterly, M. S. Taha, M. D. Tsifansky, L. T. Lyle, M. N. Seleem, Y. Yeo. (2021). Nanocapsules modify membrane interaction of polymyxin B to enable safe systemic therapy of Gram-negative sepsis. Science Advances 7 (32), eabj1577. http://doi.org/10.1126/sciadv.abj1577


164. D P Flaherty, M N Seleem, C T Supuran. (2021). Bacterial carbonic anhydrases: underexploited antibacterial therapeutic targets. Future Medicinal Chemistry fmc-2021-0207. https://doi.org/10.4155/fmc-2021-0207


163. N.S. Abutaleb, A. Elhassanny, D.P. Flaherty, M.N. Seleem. (2021). In vitro and in vivo activities of the carbonic anhydrase inhibitor, dorzolamide, against vancomycin-resistant enterococci.  PeerJ 9:e11059. https://doi.org/10.7717/peerj.11059


162. N.S. Abutaleb, and M.N. Seleem. (2021). In vivo efficacy of auranofin in a hamster model of Clostridioides difficile infection. Scientific Reports, 11: 7093 (2021). https://doi.org/10.1038/s41598-021-86595-3


161. C. Hewitt, N.S. Abutaleb, A. Elhassanny, A.  Nocentini, X. Cao, D. Amos, M. Youse, K. Holly, A. Marapaka, W. An, J. Kaur, A. Krabill, A. Elkashif, Y. Elgammal, A. L Graboski, C. T. Supuran, M. N. Seleem, D. P. Flaherty. (2021). Structure–Activity Relationship Studies of Acetazolamide-Based Carbonic Anhydrase Inhibitors with Activity against Neisseria gonorrhoeae. ACS Infectious Diseases https://doi.org/10.1021/acsinfecdis.1c00055


160. C. Ghosh, S. Varela‐Aramburu, H. E Eldesouky, S. Hossainy, M. N. Seleem, T.  Aebischer, P. H Seeberger. (2021). Non‐Toxic Glycosylated Gold Nanoparticle‐Amphotericin B Conjugates Reduce Biofilms and Intracellular Burden of Fungi and Parasites. Advanced Therapeutics, 2021,2000293. https://doi.org/10.1002/adtp.202000293


159. M. Zhang, W. Hong, N. S. Abutaleb, J. Li, P. Dong, C. Zong, P. Wang, M. N. Seleem, J. Cheng. (2021). Rapid determination of antimicrobial susceptibility by stimulated Raman scattering imaging of D2O metabolic incorporation in a single bacterium. International Society for Optics and Photonics, 11656; 116560B. https://doi.org/10.1002/advs.202001452


158. E. Coscia, N. Abutaleb, B. Hostette, M. N. Seleem, G. Breur, R. McCain, C. Crain, O. Slaby, M. Capoor, A. McDowell, F. Ahmed, V. Vijayanpillai, S. Narayanan and M. Coscia (2021). Sheep as a Potential Model of Intradiscal Infection by the Bacterium Cutibacterium acnes. Veterinary Sciences 8(48):48. https://doi.org/10.3390/vetsci8030048


157. G. A Naclerio, N. S Abutaleb, M. Alhashimi, M. N. Seleem, H. O Sintim. (2021). N-(1, 3, 4-Oxadiazol-2-yl) Benzamides as Antibacterial Agents against Neisseria gonorrhoeae. International journal of molecular sciences. 22;5;2427. https://doi.org/10.3390/ijms22052427


156. N.S. Abutaleb, A. Elkashif, D.P. Flaherty, M.N. Seleem. (2021). In vivo antibacterial activity of acetazolamide. Antimicrobial Agents and Chemotherapy 10.1128/AAC.01715-20. https://doi.org/10.1128/AAC.01715-20 


155. H. E. Eldesouky, E. A. Salama, N. A. Lanman, T. R. Hazbun, M.N. Seleem. (2021). Potent Synergistic Interactions between Lopinavir and Azole Antifungal Drugs against Emerging Multidrug-Resistant Candida auris. Antimicrobial Agents and Chemotherapy. 2021:65:1. https://doi.org/10.1128/AAC.00684-20


154. H. Mohammad, N. S. Abutaleb, A. M. Dieterly, L. T. Lyle, M.N. Seleem. (2021). Evaluation of ebselen in resolving a methicillin-resistant Staphylococcus aureus infection of pressure ulcers in obese and diabetic mice. PLoS ONE 16(2): e024750. https://doi.org/10.1371/journal.pone.0247508

2020

153. Hagras M, Abutaleb NS, N. Elhosseiny, T.  Abdelghany, M. N. Seleem, Mayhoub AS. (2020). Development of biphenylthiazoles exhibiting improved pharmacokinetics and potent activity against intracellular Staphylococcus aureus. 2020, 6, 11, 2887–2900. ACS Infectious Diseases IF= 4.614. https://doi.org/10.1021/acsinfecdis.0c00137


152. G. Naclerio, N. Abutaleb, D. Li, M. N. Seleem, H. Sintim.(2020). Ultrapotent inhibitor of Clostridioides difficile growth, which suppresses recurrence in vivo. 2020, 63, 20, 11934–11944. Journal of Medicinal Chemistry. IF=6.02. https://doi.org/10.1021/acs.jmedchem.0c01198


151. A. V. Morales-de-Echegaray, L. Lin, B. Sivasubramaniam, A. Yermembetova, Q. Wang, Abutaleb NS, M. N. Seleem. & A. Wei. (2020). Antimicrobial Photodynamic Activity of Gallium-Substituted Haemoglobin on Silver Nanoparticles. 2020,12, 21734-21742. Nanoscale. IF=6.97. https://doi.org/10.1039/C9NR09064A


150. H. Eldesouky, E. Salama, N. Lanman, T. Hazbun, M. N. Seleem. (2020). Potent synergistic interactions between lopinavir and azole antifungal drugs against emerging multidrug-resistant Candida auris. 10.1128/AAC.00684-20. Antimicrob Agents Chemother. IF= 4.715. https://doi.org/10.1128/AAC.00684-20 


149. A. Abdelkhalek and M. N. Seleem. (2020).  Repurposing the Veterinary Antiprotozoal Drug Ronidazole for the Treatment of Clostridioides difficile Infection. 2020 Oct 9;106188. International Journal of Antimicrobial Agents. IF=4.62. https://doi.org/10.1016/j.ijantimicag.2020.106188


148. J. Song, S. Malwal, N. Baig, L. Schurig-Briccio, Z. Gao, G. Vaidya, K. Yang, N. Abutaleb, M. N. Seleem, R. Gennis, T., V. Pogorelov, E. Oldfield, X. Feng. (2020). Discovery of Prenyltransferase Inhibitors with In vitro and In vivo Antibacterial Activity. 2020, 6, 11, 2979–2993. ACS Infectious Diseases IF= 4.614. https://doi.org/10.1021/acsinfecdis.0c00472


147. H. Eldesouky, N. Lanman, T. Hazbun, M. N. Seleem. (2020). Aprepitant, an antiemetic agent, interferes with metal ion homeostasis of Candida auris and displays potent synergistic interactions with azole drugs. Virulence 2020; 11(1): 1466–1481. IF=5.47. https://doi.org/10.1080/21505594.2020.1838741


146. M. G. Elnaggar, H. E. Eldesouky, Y. Pei, J. Park, H. Mohammad, Y. A. Hegazy, H. M. Tawfeek, A. A. Abdel-Rahman, A. E. Aboutaleb, M. N. Seleem, Y. Yeo. (2020). Antibacterial nanotruffles for treatment of intracellular bacterial infection. Journal: Biomaterials. August 2020, 120344. IF= 10.31. https://doi.org/10.1016/j.biomaterials.2020.120344


145. W. Zhou, A. Hsu, T. Wang, J. Jefferies, H. Mohammad, Y. Liu, Z. Luo, D. Umulis, M. N. Seleem, Q. Deng. (2020). Mitofusin 2 regulates neutrophil adhesive migration and the actin cytoskeleton. Journal of Cell Science. jcs.248880 doi: 10.1242/jcs.248880. IF= 4.57. https://doi.org/10.1242/jcs.248880

 

144. Kaur J, Cao X, Abutaleb NS, Elkashif A, Graboski AL, Tarawneh AH, Bhardwaj A, AbdelKhalek A, M. N. Seleem, Flaherty DP. (2020). Optimization of Acetazolamide-Based Scaffold as Potent Inhibitors of Vancomycin-Resistant Enterococcus. J. Med. Chem. Jul 8, 28, 2020. IF= 6.02. https://doi.org/10.1021/acs.jmedchem.0c00734


143. H. Hamann, Abutaleb NS, R. Pal, M. N. Seleem, P. V. Ramachandran. (2020). Gamma-Diaryl alpha-methylene-gamma-butyrolactones as potent antibacterials against methicillin-resistant Staphylococcus aureus. Bioorganic Chemistry.  28 August 2020, 104183. IF= 4.8. https://doi.org/10.1016/j.bioorg.2020.104183


142. M. Zhang, W. Hong, N. Abutaleb, J. Li, P. Dong, C. Zong, P. Wang, M. N. Seleem, Ji-Xin Cheng. (2020). Rapid Determination of Antimicrobial Susceptibility by Stimulated Raman Scattering Imaging of D2O Metabolic Incorporation in a Single Bacterium. Advanced Science. 2020,2001452. IF= 15.80. https://doi.org/10.1002/advs.202001452


141. M. Magana, M. Pushpanathan, A. Santos, L. Leanse, M. Fernandez, A. Ioannidis, M. Giulianotti, Y. Apidianakis, S. Bradfute, A. Ferguson, A. Cherkasov, M. N Seleem, C. Pinilla, C. Fuente-Nunez, T. Lazaridis, T. Dai, R. Houghten, R. Hancock, G. Tegos. (2020). The value of antimicrobial peptides in the age of resistance. The Lancet Infectious Diseases 3099(20)30327-3. IF= 71·421. https://doi.org/10.1016/S1473-3099(20)30327-3


140. N. S. Abutaleb & M. N. Seleem. (2020). Antivirulence activity and in vivo efficacy of auranofin against vancomycin-resistant enterococci (VRE). International Journal of Antimicrobial Agents.  55(3):105828 . IF= 4.6. https://doi.org/10.1016/j.ijantimicag.2019.10.009


139. A. Mancy, N. S. Abutaleb, M. Elsebaei, A. Yousef, A. Kotb, A. Ali, J. AbdelAleem, H. Mohammed, M. N. Seleem & A. Mayhoub. (2020). Balancing Physicochemical Properties of Phenylthiazole Compounds with Antibacterial Potency by Modifying the Lipophilic Side Chain. ACS Infectious Diseases. 6(1), pp. 80-90.  IF= 4.91. https://doi.org/10.1021/acsinfecdis.9b00211


138. J. Hui, P. Dong, L. Liang, T. Mandal, J. Li, C. Ulloa, Y. Zhan, S. Jusuf, C. Zong, M. N. Seleem, G. Liu, Q. Cui, J. Cheng. (2020). Photo-Disassembly of Membrane Microdomains Revives Conventional Antibiotics against MRSA. Advanced Science 1903117 IF= 15.80. https://doi.org/10.1002/advs.201903117


137. V. Selvamani, A. Zareei, A. Elkashif, M. K. Maruthamuthu, S. Chittiboyina, D. Delisi, Z. Li, L. Cai, V. G. Pol, M. N. Seleem, R. Rahimi. (2020). Hierarchical Micro/Mesoporous Copper Structure with Enhanced Antimicrobial Property via Laser Surface Texturing. Advanced Material Interface. 1901890. IF= 4.85. https://doi.org/10.1002/admi.201901890


136. Hagras, M., Salama, E.A., Sayed, A.M M. N. Seleem & A. Mayhoub. (2020). Oxadiazolylthiazoles as novel and selective antifungal agents. European Journal of Medicinal Chemistry 189,112046 IF= 4.81. https://doi.org/10.1016/j.ejmech.2020.112046


135. Dokla, E.M.E., Abutaleb, N.S., Milik, S.N., Abouzid, K.A.M., M. N. Seleem. (2020). Development of benzimidazole-based derivatives as antimicrobial agents and their synergistic effect with colistin against gram-negative bacteria. European Journal of Medicinal Chemistry 186,111850 IF= 4.81. https://doi.org/10.1016/j.ejmech.2019.111850


134. Vadlamani, R.A., Dhanabal, A., Detwiler, D.A., R. Pal, M. N. Seleem., Garner, A.L. (2020). Nanosecond electric pulses rapidly enhance the inactivation of Gram-negative bacteria using Gram-positive antibiotics. Applied Microbiology and Biotechnology. Volume 104, Issue 5, 1 March 2020, Pages 2217-2227. IF= 3.67. https://doi.org/10.1007/s00253-020-10365-w


133. Naclerio GA, Abutaleb NS, Onyedibe KI, M. N. Seleem and Sintim HO. (2020). Potent trifluoromethoxy, trifluoromethylsulfonyl, trifluoromethylthio and pentafluorosulfanyl containing (1,3,4-oxadiazol-2-yl) benzamides against drug-resistant Gram-positive bacteria. RSC Med. Chem. 2020,11, 102-110 IF= 3.049  https://doi.org/10.1039/C9MD00391F


132. Hammad S., Abutaleb NS, D. Li, I. Ramming, A. Shekhar, Abdel-Halim M., E. Elrazaz, M. N. Seleem, U. Bilitewski, K. Abouzid, E. El-Hossary. (2020). Synthesis and Antimicrobial evaluation of New Halogenated 1,3-Thiazolidin-4-ones. Bioorg Chem., 103517. IF= 3.9. https://doi.org/10.1016/j.bioorg.2019.103517


131. Hosny Y, Abutaleb NS, Omara M, Alhashimi M, Elsebaei MM, Elzahabi HS, N. Seleem & A. Mayhoub. (2020). Modifying the lipophilic part of phenylthiazole antibiotics to control their drug-likeness. Eur J Med Chem 2020, 185:111830. IF= 4.83. https://doi.org/10.1016/j.ejmech.2019.111830


130. H. Eldesouky, E. Salam, L. Xiaoyan, H. Mohammad, T. Hazbun, A. Mayhoub & M. N. Seleem. (2020). Repurposing approach identifies pitavastatin as a potent azole chemosensitizing agent effective against azole-resistant Candida species. Scientific reports 10 (1), 1-12 IF= 4.25. https://doi.org/10.1038/s41598-020-64571-7


129. C. Ghosh, A. AbdelKhalek, H. Mohammad, M. N. Seleem & J. Haldar. (2020) Aryl-alkyl-lysines: Novel agents for treatment of C. difficile infection. Scientific reports 10 (1), 1-7 IF= 4.25. https://doi.org/10.1038/s41598-020-62496-9


128. A. Abdelkhalek, H. Mohammad, A. Mayhoub & M. N. Seleem. (2020). Screening for potent and selective anticlostridial leads among FDA-approved drugs. The Journal of Antibiotics 73 (6), 392-409. IF= 2.60. https://doi.org/10.1038/s41429-020-0288-3


127. Young Jin Seong, A. Mayhoub, H. Mohammad & M. N. Seleem. (2020). Repurposing fenamic acids drugs to combat multidrug-resistant Neisseria gonorrhoeae. Antimicrobial Agents and Chemotherapy. 10.1128/AAC.02206-19. IF= 4.60. https://doi.org/10.1128/AAC.02206-19 


126. H. Eldesouky, E. Salam, T. Hazbun, A. Mayhoub & M. N. Seleem. (2020). Ospemifene displays broad-spectrum synergistic interactions with itraconazole through potent interference with fungal efflux activities. Scientific reports 10 (6089) IF= 4.25. https://doi.org/10.1038/s41598-020-62976-y


125. Abutaleb NS, M. N. Seleem. (2020). Repurposing the antiamoebic drug diiodohydroxyquinoline for treatment of Clostridioides difficile infections. Antimicrob Agents Chemother. 64 (6) IF= 4.715. https://doi.org/10.1128/AAC.02115-19 


124. R. Pal and M. N. Seleem (2020). Screening of Natural Products and Approved Oncology Drug Libraries for Activity against Clostridioides difficile. Scientific Reports. 10 (1), 1-8. IF= 4.25. https://doi.org/10.1038/s41598-020-63029-0


123. Mohammad, H., N. Abutaleb, M. N. Seleem. (2020). Auranofin Rapidly Eradicates Methicillin-resistant Staphylococcus aureus (MRSA) in an Infected Pressure Ulcer Mouse Model. Scientific Reports. 10 (1), 1-8 IF= 4.25. https://doi.org/10.1038/s41598-020-64352-2


122. A. Elkashif and M. N. Seleem. (2020). Investigation of auranofin and gold-containing analogues antibacterial activity against multidrug-resistant Neisseria gonorrhoeae. Scientific Reports. 10 (1), 1-9. IF= 4.25. https://doi.org/10.1038/s41598-020-62696-3


121. Thomas A. Dietsche, Eldesouky HE, M. N. Seleem, and Jean Chmielewski (2020). Targeting Intracellular Pathogenic Bacteria Through N-Terminal Modification of Cationic Amphiphilic Polyproline Helices. The Journal of Organic Chemistry. 2020, 85, 11, 7468–7475. IF= 4.8. https://doi.org/10.1021/acs.joc.0c00871


120. Abutaleb NS, M. N. Seleem. (2020). Auranofin, at clinically achievable dose, protects mice and prevents recurrence from Clostridioides difficile infection. Scientific Reports 10 (1), 1-8. IF= 4.25. https://doi.org/10.1038/s41598-020-64882-9


119.  I. Shahin, Abutaleb NS, M. Alhashimi, A. Kassab, K..Mohamed, A. Taher, N. Seleem & A. Mayhoub. (2020). Evaluation of N-Phenyl-2-aminothiazoles for Treatment of Multi-Drug Resistant and Intracellular Staphylococcus aureus Infections. Eur J Med Chem 2020, 112497. IF= 4.83. https://doi.org/10.1016/j.ejmech.2020.112497


118. A Roth, A. Elkashif, V. Selvamani, M. N. Seleem, B. Ziaie, R. Rahim. (2020). Wearable and Flexible Ozone Generating System for Treatment of Infected Dermal Wounds. Frontiers in Bioengineering and Biotechnology 8, 458. IF= 5.12. https://doi.org/10.3389/fbioe.2020.00458

2019

117. A. Abdelkhalek, N. Abutaleb, H. Mohammad & M. N. Seleem. (2019). Antibacterial and antivirulence activities of auranofin against Clostridium difficile. International Journal of Antimicrobial Agents 53: 54-62. IF= 4.30. https://doi.org/10.1016/j.ijantimicag.2018.09.018


116. S. Malwal, L. Chen, H. Hicks, F. Qu, W. Liu, A. Shillo, W. Law, J. Zhang, N. Chandnani, X. Han, Y. Zheng, C. Chen, R. Guo, A. AbdelKhalek, M. N. Seleem  & E.  Oldfield. (2019) Discovery of lipophilic bisphosphonates that target bacterial cell wall and quinone biosynthesis. Journal of Medicinal Chemistry. 62 (5), 2564-2581. IF= 6.25. https://doi.org/10.1021/acs.jmedchem.8b01878


115. A.  Kotb, N.  S.  Abutaleb, M.  Hagras, A. Bayoumi, M.  Mohamed, A. Moustafa, A. Ghiaty, M. N. Seleem & A. Mayhoub. (2019). tert-Butylphenylthiazoles with oxadiazole linker: A novel orally bioavailable class of antibiotics exhibiting antibiofilm activity. RSC Advances. 9 (12), 6770-6778. IF= 2.93. https://doi.org/10.1039/C8RA10525A


114. P. Dong, H. Mohammad, X. Wang, J. Hui, J. Li, L. Liang, M. N. Seleem & Ji-Xin Cheng. (2019). Photolysis of staphyloxanthin in methicillin-resistant Staphylococcus aureus potentiates killing by reactive oxygen species. Advanced Science. 2019, 1900030. IF= 15.80. https://doi.org/10.1002/advs.201900030


113. K. Kyei-Baffoura, H. Mohammad, M. N. Seleem & M. Dai. (2019). Second-generation aryl isonitrile compounds targeting multidrug-resistant Staphylococcus aureus. Bioorganic & Medicinal Chemistry. 27 (9), 1845-1854. IF= 2.9. https://doi.org/10.1016/j.bmc.2019.03.034


112. M. Elsebaei, H. Mohammad, N. S. Abutaleb, A. Samir, A. Norvil, A. Michie, M. Gad, H. Gowher, M. N. Seleem & A. Mayhoub. (2019). Lipophilic efficient phenylthiazoles with potent undecaprenyl pyrophosphatase inhibitory activity. European Journal of Medicinal Chemistry. 175, 49-62. IF= 4.81. https://doi.org/10.1016/j.ejmech.2019.04.063


111. H. Mohammad, K. Kyei-Baffoura, N. Abutaleb, M. Dai & M. N. Seleem (2019). An aryl isonitrile compound with an improved physicochemical profile that is effective in two mouse models of multidrug-resistant Staphylococcus aureus infection. Journal of global antimicrobial resistance. S2213-7165(19)30105-5. IF= 2.46. https://doi.org/10.1016/j.jgar.2019.04.016


110. B. Sloan, H. Mohammad, N.  S.  Abutaleb & M. N. Seleem. (2019). Comparison between a novel tap water wound irrigation device and a sterile saline device in an animal model. Trauma. 2019-3-1-6.  https://doi.org/10.1177/1460408619857399


109. M. Elsebaei, N. Abutaleb, Abdulrahman Mahgoub, D. Li, M. Hagras, H. Mohammad, M. N. Seleem & A. Mayhoub. (2019). Phenylthiazoles with Nitrogenous Side Chain: An Approach to Overcome Molecular Obesity. European Journal of Medicinal Chemistry. 19-01362. IF= 4.81. https://doi.org/10.1016/j.ejmech.2019.111593


108. X. Shao, A. Abdelkhalek, N. Abutaleb, U. Velagapudi M. N. Seleem & T. Talele. (2019). Chemical space exploration around thieno[3,2-d]pyrimidin-4(3H)-one scaffold led to a novel class of highly active Clostridium difficile inhibitors. Journal of Medicinal Chemistry. 62(21), pp. 9772-9791. IF= 6.25. https://doi.org/10.1021/acs.jmedchem.9b01198


107. A. Hammad, N. S. Abutaleb, M. Elsebaei, M. Ali, M.  Al-Sawah, M. N. Seleem & A. Mayhoub. (2019). From phenylthiazoles to phenylpyrazoles: Broaden the antibacterial spectrum towards carbapenam-resistant strains. Journal of Medicinal Chemistry. 62(17), pp. 7998-8010 IF= 6.25. https://doi.org/10.1021/acs.jmedchem.9b00720


106. N. Dayal, C. Opoku-Temeng, H. Mohammad, N. S. Abutaleb, D. Hernandez, M. N. Seleem & H. Sintim. (2019). Inhibitors of Intracellular Gram-Positive Bacterial Growth Synthesized via Povarov−Doebner Reactions. ACS Infectious Diseases. 5(11), pp. 1820-1830. IF= 4.91. https://doi.org/10.1021/acsinfecdis.9b00022


105. S. Al-Trawneh, N.  Abutaleb, E. Salama, A. Tarawneh, and M. N. Seleem. (2019). Synthesis of New Pyrazolo Triazines with antifungal antibiofilm activity. Medicinal Chemistry Research. MCRE-D-19-00300 IF= 1.7. https://doi.org/10.1007/s11696-019-00974-9


104. D. Mody, A. Athamneh, & M. N. Seleem. (2019). Curcumin: A natural derivative with antibacterial activity against Clostridium difficile. Journal of Global Antimicrobial Resistance. JGAR-D-19-00442. IF= 2.9. https://doi.org/10.1016/j.jgar.2019.10.005


103. M. Alhashimi & M. N. Seleem. (2019). Repurposing salicylamide for combating multidrug-resistant Neisseria gonorrhoeae. Antimicrobial Agents and Chemotherapy 63(12),e01225-19. IF= 4.7.  https://doi.org/10.1128/AAC.01225-19 


102. Mohammad, H., Eldesouky, H.E., Hazbun, T., Mayhoub, A.S., M. N. Seleem. (2019). Identification of a Phenylthiazole Small Molecule with Dual Antifungal and Antibiofilm Activity Against Candida albicans and Candida auris. Scientific Reports 9(1),18941 IF= 4.25. https://doi.org/10.1038/s41598-019-55379-1

2018

101. M. Hagras, Y. Hegazy, A. Elkabbany, H. Mohammad, A. Ghiaty, T. Abdelgahny & M. N. Seleem & A. Mayhoub. (2018). Biphenylthiazole antibiotics with an oxadiazole linker: An approach to improve physicochemical properties and oral bioavailability. European Journal of Medicinal Chemistry. 143: 1448-1456. IF= 4.81. https://doi.org/10.1016/j.ejmech.2017.10.048


100. H. Eldesouky, A. Mayhoub, T. R. Hazbun & M. N. Seleem. (2018). Reversal of azole resistance in Candida albicans by sulfa antibacterial drugs. Antimicrobial Agents and Chemotherapy 62 (3): e00701-17. IF= 4.45. https://doi.org/10.1128/AAC.00701-17 


99. H. Mohammad, A. Abdelkhalek, N. Abutaleb & M. N. Seleem. (2018). Evaluation of the anthelmintic drug niclosamide for intestinal decolonization of vancomycin-resistant Enterococci. International Journal of Antimicrobial Agents 51 (6): 897-904. IF= 4.30. https://doi.org/10.1016/j.ijantimicag.2018.02.003


98. W. Hong, C. W. Karanja, W. Younis, X. Zhang, M. N. Seleem & Ji-Xin Cheng. (2018). Antibiotic susceptibility determination within one cell cycle at single bacterium level by stimulated Raman metabolic imaging. Analytical Chemistry 90(6):3737-3743 IF= 6.32. https://doi.org/10.1021/acs.analchem.7b03382


97. H. Mohammad, N. ElGhazawy, H. Eldesouky, Y. Hegazy, W. Younis, L. Avrimova, T. Hazbun, R. Arafa & M. N. Seleem. (2018). Discovery of a novel dibromoquinoline compound exhibiting potent antifungal and antivirulence activity that targets metal ion homeostasis. ACS Infectious Diseases. 4 (3): 403-414 IF= 4.91. https://doi.org/10.1021/acsinfecdis.7b00215


96. M. M. Elsebaei, H. Mohammad, M. Abouf, N. Abutaleb, Y. Hegazy, A. Ghiaty, L. Chen, J. Zhang, E. Oldfield, M. N. Seleem & A. Mayhoub.(2018). Alkynyl-containing phenylthiazoles: Systemically active antibacterial agents effective against methicillin-resistant Staphylococcus aureus (MRSA). European Journal of Medicinal Chemistry 148: 195-209. IF= 4.81. https://doi.org/10.1016/j.ejmech.2018.02.031


95. B. E. Bergstrom, A. Abdelkhalek, W. Younis, G. K. Hammac, W. M. Townsend & M. N. Seleem. (2018). Antibacterial activity and safety of commercial veterinary cationic steroid antibiotics and neutral superoxidized water. PloS One 13(3):e0193217. IF= 2.8. https://doi.org/10.1371/journal.pone.0193217


94. C. Opoku-Temeng, H. Mohammad, N. Dayal, G. Naclerio, N. Abutaleb , M. N. Seleem & H. Sintim. (2018). N-(1,3,4-oxadiazol-2-yl)benzamide analogs, bacteriostatic agents against methicillin- and vancomycin-resistant bacteria. European Journal of Medicinal Chemistry. 155: 797-805. IF= 4.81. https://doi.org/10.1016/j.ejmech.2018.06.023


93. A. Kotb, N. Abutaleb, M. Seleem, M. Hagras, H. Mohammad, A. Bayoumi, A. Ghiaty, M. N. Seleem & A. Mayhoub.(2018). Phenylthiazoles with tert-Butyl Side Chain: Metabolically stable with anti-biofilm activity. European Journal of Medicinal Chemistry. 151; 110-120. IF= 4.81 . https://doi.org/10.1016/j.ejmech.2018.03.044


92. M. Awamy, H. Mohammad, A. Hussien, N. Abutaleb,  M. Hagras, R. Serya, A. Taher, K. Abuzaid, M. N. Seleem & A. Mayhoub.(2018). Alkoxyphenylthiazoles with broad-spectrum activity against multidrug-resistant Gram-positive bacterial pathogens. European Journal of Medicinal Chemistry. 152: 318-328. IF= 4.81. https://doi.org/10.1016/j.ejmech.2018.04.049


91. A. Abdelkhalek, N. Abutaleb, K. Elmagarmid & M. N. Seleem. (2018). Repurposing auranofin as an intestinal decolonizing agent for vancomycin-resistant Enterococci. Scientific Reports 8 (1): 8353 IF= 4.25. https://doi.org/10.1038/s41598-018-26674-0


90. M. Nepal, M. Mohamed, R. Blade, H. Eldesouky, T. Anderson, M. N. Seleem & J. Chmielewski (2018).  A library approach to cationic amphiphilic polyproline helices that target intracellular pathogenic bacteria. ACS Infectious Diseases 4; 1300-1305. IF= 4.91. https://doi.org/10.1021/acsinfecdis.8b00124


89. A. Abdelkhalek, N. Abutaleb, H. Mohammad & M. N. Seleem. (2018). Repurposing ebselen for decolonization of vancomycin-resistant enterococci (VRE). PloS One 13 (6): e0199710 IF= 2.8. https://doi.org/10.1371/journal.pone.0199710


88. H. Eldesouky, L. Xiaoyan, N. Abutaleb, H. Mohammad & M. N. Seleem. (2018). Synergistic interactions of sulfamethoxazole and azole antifungal drugs against emerging multidrug-resistant Candida auris. International Journal of Antimicrobial Agents. 52 (6): 754-761 IF= 4.30. https://doi.org/10.1016/j.ijantimicag.2018.08.016


87. A. Morales, T. Maltais, L. Lu, W. Younis, N. Kadasala, M. N. Seleem & A. Wei. (2018). Rapid uptake and photodynamic inactivation of Staphylococci by ga(III)-protoporphyrin IX. ACS Infectious Diseases 11; 1564-1573. IF= 4.82. https://doi.org/10.1021/acsinfecdis.8b00125

2017

86. E. Yahia, H. Mohammad, T. Abdelghany, E. Fayed, M. N. Seleem & A. Mayhoub. (2017). Phenylthiazole antibiotics: A metabolism-guided approach to overcome short duration of action. European Journal of Medicinal Chemistry 126: 604-61. IF= 4.81. https://doi.org/10.1016/j.ejmech.2016.11.042


85. S. Thangamani, M. Maland, H. Mohammad, P. Pascuzzi , L. Avramova, C. Koehler, T. Hazbun & M. N. Seleem. (2017). Repurposing approach identifies auranofin with broad spectrum antifungal activity that targets Mia40-Erv1 pathway. Frontiers in Cellular and Infection Microbiology 7:4. IF= 4.3. https://doi.org/10.3389/fcimb.2017.00004


84. W. Younis, A. AbdelKhalek, A. Mayhoub & M. N. Seleem. (2017). In vitro screening of an FDA-approved library against ESKAPE pathogens. Current pharmaceutical design 23(14):2147-2157. IF= 3.052.  http://doi.org/10.2174/1381612823666170209154745


83. C. Ghosh, V. Yadav, W. Younis, H. Mohammad, Y. Hegazy, M.N. Seleem, K. Sanyal & J. Haldar. (2017). Aryl-alkyl-lysines: Membrane-active fungicides that act against biofilms of Candida albicans. ACS Infectious Diseases 3(4):293-301. IF= 4.91. https://doi.org/10.1021/acsinfecdis.6b00192


82. I. Eissa, H. Mohammad, O. Qassem, W. Younis, T. Abdelghany, A. Elshafeey, M. Moustafa, M.N. Seleem & A. Mayhoub. (2017). Diphenylurea derivatives for combating methicillin-and vancomycin-resistant Staphylococcus aureus. European Journal of Medicinal Chemistry 130; 73-85. IF= 4.81. https://doi.org/10.1016/j.ejmech.2017.02.044


81. H. Mohammad, K. Kyei-Baffourb, W. Younis, D. Davis, H. Eldesouky, M. N. Seleem & M. Dai. (2017). Investigation of aryl isonitrile compounds with potent, broad-spectrum antifungal activity. Bioorganic & Medicinal Chemistry 25:2926–2931. IF= 3.79. https://doi.org/10.1016/j.bmc.2017.03.035


80. S. Thangamani, H. Eldesouky, H. Mohammad, P. Pascuzzi, L. Avramova, T. Hazbun & M.N. Seleem. (2017). Ebselen exerts antifungal activity by regulating glutathione (GSH) and reactive oxygen species (ROS) production in fungal cells. Biochimica et Biophysica Acta (BBA)-General Subjects 1861 (1): 3002-3010. IF= 4.70. https://doi.org/10.1016/j.bbagen.2016.09.029


79. M. Mohamed, A. Brezden, H. Mohammad, J. Chmielewski & M.N. Seleem. (2017). Targeting biofilms and persisters of ESKAPE pathogens with P14KanS, a kanamycin peptide conjugate. Biochimica et Biophysica Acta (BBA)-General Subjects 1861 (4): 848-859. IF= 4.70. https://doi.org/10.1016/j.bbagen.2017.01.029


78. H. Mohammad, W. Younis, L. Chen, C. Peters, J. Pogliano, K. Pogliano, B. Cooper, J. Zhang, A. Mayhoub, E. Oldfield, M. Cushman & M.N. Seleem. (2017). Phenylthiazole antibacterial agents targeting cell wall synthesis exhibit potent activity in vitro and in vivo against vancomycin-resistant enterococci. Journal of Medicinal Chemistry 60(6):2425-2438. IF= 6.25. https://doi.org/10.1021/acs.jmedchem.6b01780


77. M. Hagras, H. Mohammad, M. Mandour, Y. Hegzy, A. Ghiaty, M. N. Seleem & A. Mayhoub. (2017). Investigating the antibacterial activity of biphenylthiazoles against methicillin- and vancomycin-resistant Staphylococcus aureus (MRSA and VRSA). Journal of Medicinal Chemistry. 60 (9): 4074–4085. IF= 6.25. https://doi.org/10.1021/acs.jmedchem.7b00392


76. X. Yin, H. Mohammed, H. Eldesouky, A. Hassan, M. N. Seleem & M. Dai. (2017). Rapid synthesis of vicyclic lactones via palladium-catalyzed aminocarbonylative lactonizations. Chemical Communications. 53;7238-7241. IF= 6.319. https://doi.org/10.1039/C7CC02494K


75. M. Mohamed, A. Brezden, H. Mohammad, J. Chmielewski & M.N. Seleem. (2017). A short D-enantiomeric antimicrobial peptide with potent immunomodulatory and antibiofilm activity against multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii. Scientific Reports 7: 6953. IF= 4.25. https://doi.org/10.1038/s41598-017-07440-0


74. H. Hussain, Z. Iqbal, M. N. Seleem, D. Huang, A. Sattar, H. Hao & Z.  Yuan. (2017). Virulence and transcriptome profile of multidrug-resistant Escherichia coli from chicken. Scientific Reports. 7: 8335. IF= 4.25. https://doi.org/10.1038/s41598-017-07798-1


73. Y. Pei, M. F. Mohamed, M. N. Seleem & Y. Yeo. (2017). Particle engineering for intracellular delivery of vancomycin to methicillin-resistant Staphylococcus aureus (MRSA)-infected macrophages. The Journal of Controlled Release. 267; 133-143. IF= 7.87 . https://doi.org/10.1016/j.jconrel.2017.08.007


72. H. Mohammad, W. Younis, H. Ezzat, C. Peters, A. Abdelkhalek, J. Pogliano, K. Pogliano, B. Cooper, A. Mayhoub & M. N. Seleem. (2017). Diphenylurea compounds targeting bacterial cell wall synthesis exhibit potent antibacterial activity. PLoS One. 12(8):e0182821. IF= 2.8. https://doi.org/10.1371/journal.pone.0182821


71. M. I. Hamed, T. L. McCalla, W. M. Townsend & M. N. Seleem. (2017). Staphylococcus pseudintermedius Isolated from Two Dog Cases with Ophthalmic Lesions. American Journal of Infectious Diseases and Microbiology, 5(4): 132-136. http://pubs.sciepub.com/ajidm/5/4/2


70. C. W. Karanja, W. Hong, W. Younis, H. Eldesouky, M. N. Seleem & Ji-Xin Cheng. (2017). Stimulated Raman imaging reveals aberrant lipogenesis as a metabolic marker for azole-resistant Candida albicans. Analytical Chemistry. 18; 9822-9829. IF= 6.32. https://doi.org/10.1021/acs.analchem.7b01798


69. I. Eid, M. Elsebaei, H. Mohammad, M. Hagras, C. E. Peters, Y. Hegazy, B. Cooper, J. Pogliano, K. Pogliano, H. S. Abulkhair, M. N. Seleem & A. Mayhoub.  (2017). Arylthiazole Antibiotics Targeting Intracellular Methicillin-resistant Staphylococcus aureus (MRSA) Interfere with Bacterial Cell Wall Synthesis. European Journal of Medicinal Chemistry.139; 665-673. IF= 4.81. https://doi.org/10.1016/j.ejmech.2017.08.039

2016

68. M. Abushahba, H. Mohammad, S. Thangamani, A. Hussein & M. N. Seleem. (2016). Impact of different cell penetrating peptides on the efficacy of antisense therapeutics for targeting intracellular pathogens. Scientific Reports 6: 20832. IF= 4.25. https://doi.org/10.1038/srep20832


67. S. Thangamani, H. Mohammad, M. Abushahba, T. Sobreira & M. N. Seleem. (2016). Repurposing auranofin for the treatment of cutaneous staphylococcal infections. International journal of antimicrobial agents 47 (3): 195-201. IF= 4.30. https://doi.org/10.1016/j.ijantimicag.2015.12.016


66. S. Thangamani, H. Mohammad, M. Abushahba, T. Sobreira, V Hedrick, L. Paul & M. N. Seleem. (2016). Antibacterial activity and mechanism of action of auranofin against multi-drug resistant bacterial pathogens. Scientific Reports 6: 22571. IF= 4.25. https://doi.org/10.1038/srep22571


65. W. Hong, C. Liao, H. Zhao, W. Younis, Y. Zhang, M. N. Seleem & J. Cheng. (2016). In situ detection of a single bacterium in complex environment by hyperspectral CARS imaging. ChemistrySelect 3: 513–517 IF 1.505 . https://doi.org/10.1002/slct.201600166


64. M. Seleem, A. Disouky, H. Mohammad, T. Abdelghany, A. Mancy, S. Bayoumi, A. Elshafeey, A. El-Morsy, M. N. Seleem & A. S. Mayhoub. (2016). Second-generation phenylthiazole antibiotics with enhanced pharmacokinetic properties. Journal of Medicinal Chemistry 59(10):4900-12. IF= 6.25. https://doi.org/10.1021/acs.jmedchem.6b00233


63. M. Abushahba, H. Mohammad & M. N. Seleem (2016). Targeting multidrug-resistant Staphylococci with an anti-rpoA peptide nucleic acid conjugated to the HIV-1 TAT cell penetrating peptide. Molecular Therapy—Nucleic Acids 5 (7): e339. IF= 6.39. https://doi.org/10.1038/mtna.2016.53


62. M. Abushahba, A. Hussein, M. N. Seleem & R Hassanein. (2016). Listeria monocytogenes: Overview and Targeting Advances. Journal of Advanced Veterinary Research 6 (2): 72-80. https://advetresearch.com/index.php/AVR/article/view/30/26


61. T. Maltais, A. Adak, W. Younis, M. N. Seleem & A. Wei. (2016). Label-Free detection and discrimination of bacterial pathogens based on hemin recognition. Bioconjugate Chemistry 27 (7): 1713–1722. IF= 4.81. https://doi.org/10.1021/acs.bioconjchem.6b00236


60. A. AbdelKhalek, C. Ashby, B. Patel, T. Talele & M. N. Seleem. (2016). In vitro antibacterial activity of rhodanine derivatives against pathogenic clinical isolates. PLoS One 11(10):e0164227. IF= 2.8. https://doi.org/10.1371/journal.pone.0164227


59. A. Brezden, M. Mohamed, M. Nepal, J. Harwood, J. Kuriakose, M. N. Seleem & J. Chmielewski. (2016). Dual targeting of intracellular pathogenic bacteria with a cleavable conjugate of kanamycin and an antibacterial, cell penetrating peptide. Journal of the American Chemical Society 138 (34): 10945–10949. IF= 14.35. https://doi.org/10.1021/jacs.6b04831


58. W. Younis, H. Mohammad, M. Hostetler, D. López-Pérez, C. Steussy, M. Lipton, C. Stauffacher, S. Sultan, M. Wael, A. Hussein & M. N. Seleem . (2016). Class II HMG-CoA reductase inhibitors targeting methicillin-resistant Staphylococcus pseudintermedius. Journal of Advanced Veterinary Research (7)1: 1-6.  https://advetresearch.com/index.php/AVR/article/view/3/3


57. Z. Iqbal, M. N. Seleem, H. Iftikhar H. Huang, H. Hao & Z. Yuan. (2016). Comparative virulence studies and transcriptome analysis of Staphylococcus aureus strains isolated from animals. Scientific Reports 6: 35442. IF= 4.25. https://doi.org/10.1038/srep35442


56. M. Mohamed, A. Abdelkhalek & M. N. Seleem. (2016). Evaluation of short synthetic antimicrobial peptides for treatment of drug-resistant and intracellular Staphylococcus aureus. Scientific Reports 6: 29707. IF= 4.25. https://doi.org/10.1038/srep29707

2015

55. S. Thangamani, H. Mohammad, M. Abushahba, M. Hamed, T. Sobreira, V. Hedrick, L. Paul & M. N. Seleem. (2015). Exploring simvastatin, an antihyperlipidemic drug, as a potential topical antibacterial agent. Scientific Reports 5: 16407. IF= 4.25. https://doi.org/10.1038/srep16407 


54. H. Mohammad, M. Cushman & M. N. Seleem. (2015). Antibacterial evaluation of synthetic thiazole compounds in vitro and in vivo in a methicillin-resistant Staphylococcus aureus (MRSA) Skin Infection Mouse Model. PLoS One 10(11):e0142321. IF= 2.8. https://doi.org/10.1371/journal.pone.0142321


53. S. Thangamani, M. Nepal, J. Chmielewsk & M. N. Seleem. (2015). Antibacterial activity and therapeutic efficacy of Fl-PRPRPL-5, a cationic amphiphilic polyproline helix, in a mouse model of staphylococcal skin infection. Drug Design, Development and Therapy 9: 5749—5754. IF= 3.02. https://doi.org/10.2147/DDDT.S94505


52. S. Thangamani, W. Younis & M. N. Seleem. (2015). Repurposing celecoxib as a topical antimicrobial agent. Frontiers Microbiology 28: 6:750. IF= 4.16. https://doi.org/10.3389/fmicb.2015.00750


51. S. Thangamani, W. Younis & M. N. Seleem. (2015). Repurposing clinical molecule ebselen to combat drug resistant pathogens. PLoS One 10 (7):e0133877. IF= 2.8. https://doi.org/10.1038/srep11596


50. W. Younis, S. Thangamani & M. N. Seleem. (2015). Repurposing Non-antimicrobial Drugs and Clinical Molecules to Treat Bacterial Infections. Current Pharmaceutical Design 21(28):4106-11. IF= 3.052. http://doi.org/10.2174/1381612821666150506154434


49. Dabral N, Jain-Gupta N, M. N. Seleem, Sriranganathan N & Vemulapalli R. (2015). Overexpression of Brucella putative glycosyltransferase WbkA in Brucella abortus RB51 leads to production of exopolysaccharide. Frontiers in Cellular and Infection Microbiology 24;5:54. IF= 4.3. https://doi.org/10.3389/fcimb.2015.00054


48. Davis DC, Mohammad H, Kyei-Baffour K, Younis W, Creemer CN, M. N. Seleem & Dai M. (2015). Discovery and characterization of aryl isonitriles as a new class of compounds versus methicillin- and vancomycin-resistant Staphylococcus aureus. European Journal of Medicinal Chemistry 101:384-390. IF= 4.81. https://doi.org/10.1016/j.ejmech.2015.06.031


47. S. Thangamani, W. Younis & M. N. Seleem. (2015). Repurposing ebselen for treatment of multidrug-resistant staphylococcal infections. Scientific Reports 5:11596. IF= 4.25. https://doi.org/10.1038/srep11596


46. M. Nepal, S. Thangamani, M. N. Seleem & J. Chmielewski. (2015). Targeting intracellular bacteria with an extended cationic amphiphilic polyproline helix. Organic & Biomolecular Chemistry 13 (21):5930-6. IF= 3.56. https://doi.org/10.1039/C5OB00227C


45. H. Mohammad, PV Reddy, D. Montelenoe, AS Mayhoub, M. Cushman, GK Hammac & M. N. Seleem. (2015). Antibacterial Characterization of Novel Synthetic Thiazole compounds against methicillin-resistant Staphylococcus pseudintermedius. PLoS One 10(6):e0130385. IF= 2.8. https://doi.org/10.1371/journal.pone.0130385


44. Mohammad, H., Reddy, P.V.N., Monteleone, D., Cushman, M., & M. N. Seleem. (2015). Synthesis and antibacterial evaluation of a novel series of synthetic phenylthiazole compounds against methicillin-resistant Staphylococcus aureus (MRSA). European Journal of Medicinal Chemistry 94:306-316. IF= 4.81. https://doi.org/10.1016/j.ejmech.2015.03.015


43. H. Mohammad, S. Thangamani & M. N. Seleem. (2015). Antimicrobial peptides and peptidomimetics-potent therapeutic allies for staphylococcal infections. Current Pharmaceutical Design 21 (16): 2073-2088. IF= 3.052 (invited review article) . http://doi.org/10.2174/1381612821666150310102702


42. S. Thangamani, H. Mohammad, W. Younis & M. N. Seleem. (2015). Repurposing non-antimicrobial drugs for treatment of staphylococcal infections. Current Pharmaceutical Design 21 (16): 2089-2100. IF= 3.052 (invited review article). http://doi.org/10.2174/1381612821666150310104416


41. H. Mohammad, A. S. Mayhoub, M. Cushman & M. N. Seleem. (2015). Anti-biofilm activity and synergism of novel thiazole compounds with glycopeptide antibiotics against multidrug-resistant staphylococci. Nature Journal of Antibiotics 68(4):259-66. IF= 2.23. https://doi.org/10.1038/ja.2014.142

2014

40. E. A. Swanson, L. J. Freeman, M. N. Seleem & P. W. Snyder. (2014). Biofilm-infected wounds in a dog: Case report and review of the literature. Journal of the American Veterinary Medical Association 244(6): 699-707. IF=1.67 . https://doi.org/10.2460/javma.244.6.699


39. W. Lv, B. Banerjee, K. Molland, M. N. Seleem, A. Ghafoor, M. Hamed, B. Wan, S. Franzblau & A.  Mesecar, M. Cushman. (2014). Synthesis and Antibacterial Activity of 3-(3-Aryl-pyrrolidin-1-yl)-5-aryl-1,2,4-triazine Inorganic Pyrophosphatase Inhibitors. Bioorganic & Medicinal Chemistry 22 (1): 406-18. IF=2.95. https://doi.org/10.1016/j.bmc.2013.11.011


38. H. Mohammad, A. S. Mayhoub, A. Ghafor, M. Soofi, R. Alajlouni, M. Cushman & M. N. Seleem. (2014). Discovery and characterization of potent substituted thiazole compounds versus methicillin-and vancomycin-resistant Staphylococcus aureus. Journal of Medicinal Chemistry 57 (4): 1609–1615. IF= 6.25. https://doi.org/10.1021/jm401905m


37. A. Athamneh, R. Alajlouni, R. S. Wallace, M. N. Seleem & Ryan Senger. (2014). Phenotypic profiling of antibiotic response signatures in Escherichia coli using Raman spectroscopy. Antimicrobial Agents and Chemotherapy 58 (3): 1302–1314. IF=4.45 . https://doi.org/10.1128/AAC.02098-13


36. M. F. Mohamed, M. I. Hamed, A. Panitch & M. N. Seleem. (2014).Targeting methicillin-resistant Staphylococcus aureus with short synthetic peptides: coupling membrane disruption with DNA binding. Antimicrobial Agents and Chemotherapy 58 (7): 4113-4122. IF= 4.45 . https://doi.org/10.1128/AAC.02578-14 


35. M. F. Mohamed & M. N. Seleem. (2014). Efficacy of short novel antimicrobial and anti-inflammatory peptides in a mouse model of methicillin-resistant Staphylococcus aureus (MRSA) skin infection. Drug Design, Development and Therapy 8: 1979-1983. IF= 3.02. https://doi.org/10.2147/DDDT.S72129


34. M. F. Mohamed, G. K. Hammac, L. Guptill & M. N. Seleem. (2014). Antibacterial activity of novel cationic peptides against clinical isolates of multi-drug resistant staphylococcus pseudintermedius from infected dogs. PLoS One 9(12):e116259. IF= 2.80. https://doi.org/10.1371/journal.pone.0116259

2011-2013

33. N. Jain, A. Contreras, G. Kimswade, M. N. Seleem, S. M. Boyle & N. Sriranganathan. (2011). Effect of entF deletion on iron acquisition and erythritol metabolism by Brucella abortus 2308. FEMS Microbiology Letters 316 (1):1-6. IF= 2.72. https://doi.org/10.1111/j.1574-6968.2010.02186.x


32. P. Rajasekaran, N. Surendran, M. N. Seleem, N. Sriranganathan, G. G. Schurig & S. M. Boyle. (2011). Over-expression of homologous antigens in a leucine auxotroph of Brucella abortus strain RB51 protects mice against a virulent Brucella suis challenge. Vaccine 29 (17):3106-3110. IF= 3.48. https://doi.org/10.1016/j.vaccine.2011.02.054 


31. A. Ranjan, N. Pothayee, M. N. Seleem, S. M. Boyle, R. Kasimanickam, J. S. Riffle &N. Sriranganathan . (2012). Nanomedicine for intracellular therapy. FEMS Microbiology letters 332 (1):1-9. IF=2.72. https://doi.org/10.1111/j.1574-6968.2012.02566.x


30. M. Soofi & M. N. Seleem. (2012). Targeting Salmonella essential genes with antisense peptide nucleic acid. Antimicrobial Agents and Chemotherapy 56 (12): 6407-9.  IF= 4.45 .  https://doi.org/10.1128/AAC.01437-12 


29. P. Rajesekaran, J. Alexander, M. N. Seleem, N. Jain, N. Sriranganathan, A. Wattam, J. Setubal & S. M. Boyle. (2013). Peptide nucleic acids inhibit Brucella suis in pure culture and infected macrophages. International Journal of Antimicrobial Agents 41 (4): 358-62. IF= 4.3. https://doi.org/10.1016/j.ijantimicag.2012.11.017 


28. R. Alajlouni & M. N. Seleem. (2013). Targeting Listeria monocytogenes rpoA and rpoD genes using peptide nucleic acid. Nucleic Acid Therapeutics 23(5): 363-7. IF=2.88. https://doi.org/10.1089/nat.2013.0426


27. J. Kuriakose, V. Hernandez-Gordillo, M. Nepal, A.a Brezden, V. Pozzi, M. N. Seleem, & J. Chmielewski. (2013). Targeting intracellular pathogenic bacteria with unnatural proline-rich peptides: coupling antibacterial activity with macrophage penetration. Angewandte Chemie International Edition 52(37):9664-7. IF=12.1. https://doi.org/10.1002/anie.201302693

2004-2010

26. M. N. Seleem, R. Vemulapalli, S. M. Boyle, G. G. Schurig & N. Sriranganathan. (2004). Improved expression vector for Brucella species. BioTechniques 37 (5): 740-744. IF= 2.75. https://doi.org/10.2144/04375BM05


25. A. Bandara, M. N. Seleem, C. Jordan, D. Lindsay, G. G. Schurig, & N. Sriranganathan. (2006). Brucella abortus strain RB51 can be used to express potentially protective antigens of Toxoplasma gondii. Journal of eukaryotic microbiology 53 (S1): S166–S168. IF= 2.91. https://doi.org/10.1111/j.1550-7408.2006.00218.x


24. A. Contreras, M. N. Seleem, S. M. Boyle, G. G. Schurig, N. Sriranganathan & A. Lopez-merino. (2006). Cloning, expression and characterization of immunogenic aminopeptidase N from Brucella melitensis. FEMS Immunology and Medical Microbiology 48 (2): 252-256. IF= 3.07. https://doi.org/10.1111/j.1574-695X.2006.00145.x 


23. M. N. Seleem, M. Ali, S. M. Boyle, B. Mukhopadhyay, S. G.  Witonsky, G. G. Schurig & N. Sriranganathan. (2006). Establishment of gene expression system in Ochrobactrum anthropi. Applied and Environmental Microbiology 72 (10): 6833-6836. IF= 3.95 . https://doi.org/10.1128/AEM.01446-06 


22. M. N. Seleem, M. Ali, M. Abd Alazim, S. M. Boyle & N. Sriranganathan. (2007). High-level heterologous gene expression in Ochrobactrum anthropi using an A-rich UP element. Applied Microbiology and Biotechnology 73 (5):1123-1127. IF=3.81. https://doi.org/10.1007/s00253-006-0555-7


21. M. N. Seleem, M. Ali, M. Abd Alazim, S. M. Boyle & N. Sriranganathan. (2007). Enhanced expression, detection and purification of recombinant protein using tandem fusion tags RNA stem loop. Applied Microbiology and Biotechnology 75 (6):1385-1392. IF=3.81. https://doi.org/10.1007/s00253-007-0970-4


20. M. N. Seleem, S. M. Boyle & N. Sriranganathan. (2008). Brucella; a pathogen without classical virulence genes. Veterinary Microbiology 129 (1-2):1-14. IF=2.72. https://doi.org/10.1016/j.vetmic.2007.11.023


19. M. N. Seleem, P. Rajasekaran, M. Ali, S. M. Boyle & N. Sriranganathan. (2008). Simple Method for Transformation of Ochrobactrum anthropi. World Journal of Microbiology and Biotechnology 24 (10): 2111-2114. IF=2.10. https://doi.org/10.1007/s11274-008-9716-4

18. I. Sandal, M. N. Seleem, Elswaifi, N. Sriranganathan & T. Inzana. (2008). Construction of a high-efficiency shuttle vector for Histophilus somni. Journal of Microbiological Methods 74 (2-3):106-109. IF=2.09. https://doi.org/10.1016/j.mimet.2008.04.002


17. M. N. Seleem, M. Ali, S.M. Boyle & N. Sriranganathan. (2008). Vectors for enhanced gene expression and protein purification in Salmonella. Gene 421 (1-2): 95-98. IF=2.49. https://doi.org/10.1016/j.gene.2008.06.021

16. N. Pothayee, M. L. Vadala, A. Ranjan, N. Jain, M. N. Seleem, N. Sriranganathan & J. S. Riffle. (2008). Aminoglycoside-Ionopolymeric nanoplexes for targeting intracellular bacterial pathogens. Polymer Preprints 49 (2): 1036-1037. IF not determined. https://doi.org/10.1128/AAC.45.11.2977-2986.2001 


15. M. N. Seleem, M. Ali, S. M. Boyle & N. Sriranganathan. (2008). Reporter genes for real-time in vivo monitoring of Ochrobactrum anthropi infection. FEMS Microbiology letters 286 (1):124-129. IF= 2.72. https://doi.org/10.1111/j.1574-6968.2008.01270.x


14. P. Rajasekaran, M. N. Seleem, A. Contreras, N. Sriranganathan & S. Boyle. (2008). A leucine auxotroph of Brucella abortus strain RB51 vaccine as an environmentally safe vector for plasmid maintenance and antigen expression. Applied and Environmental Microbiology 74 (22): 7051-7055. IF= 3.95 .  https://doi.org/10.1128/AEM.01511-08 


13. M. N. Seleem, N. Jain, H. Alqublan, R. Vemulapalli, S. M. Boyle, & N. Sriranganathan. (2008). Activity of native vs. synthetic promoters in Brucella. FEMS Microbiology Letters 288 (2): 211-215. IF= 2.72. https://doi.org/10.1111/j.1574-6968.2008.01358.x

12. P. Munusamy, M. N. Seleem, H. Alqublan, R. Tyler, N. Sriranganathan & G. Pickrell. (2009). Targeted drug delivery using silica xerogel systems to treat diseases due to intracellular pathogens. Material Science and Engineering C 29 (8): 2313-2318. IF=5.08. https://doi.org/10.1016/j.msec.2009.05.020


11. M. N. Seleem, Jain N., N. Pothayee., Ranjan A, J. Riffle & N. Sriranganathan. (2009). Targeting Brucella melitensis with polymeric nanoparticles containing streptomycin and doxycycline. FEMS Microbiology Letters 294 (1): 24-31. IF= 2.72. https://doi.org/10.1111/j.1574-6968.2009.01530.x

10. A. Ranjan, N. Pothayee, M. N. Seleem, R. Tyler, N. Sriranganathan, R. Kasimanickam, M. Makris & J. S. Riffle. (2009). Antibacterial efficacy of core-shell nanostructures encapsulating gentamicin against in vivointracellular Salmonella model. International Journal of Nanomedicine(4): 289-297. IF=4.37. https://doi.org/10.2147/IJN.S7137


9. P. Munusamy, M. N. Seleem, N. Sriranganathan & G. Pickrell. (2009). Synthesis and characterization of Magnetic Silica Xerogels for Targeting Intracellular Pathogens. Journal of Bionanoscience3 (1):16–21. IF not determined. https://doi.org/10.1166/jbns.2009.1004

8. A. Ranjan, N. Pothayee, M. N. Seleem, N. Sriranganathan, R. Kasimanickam, M. Makris & J. S. Riffle. (2009). In-vitro trafficking and efficacy of core-shell nanostructures for treating intracellular Salmonella. Antimicrobial Agents and Chemotherapy 53 (9): 3985-3988. IF= 4.45 . https://doi.org/10.1128/AAC.00009-09 


7. D. Gillaspie, I. Perkins, K. Larsen, A. McCord, S. Pangonis, D. Sweger, M. N. Seleem, N. Sriranganathan, & B. Anderson. (2009). Plasmid based system for high-level gene expression and antisense gene knockdown in Bartonella. Applied and Environmental Microbiology75 (16):5434-5436. IF=3.95 . https://doi.org/10.1128/AEM.00949-09 


6. M. N. Seleem, P. Munusamy, A. Ranjan, H. Alqublan, G. Pickrell & N. Sriranganathan. (2009). Silica-antibiotic hybrid nanoparticles for targeting intracellular pathogens. Antimicrobial Agents and Chemotherapy 53 (10):4270-4274. IF= 4.45 . https://doi.org/10.1128/AAC.00815-09 


5. M. N. Seleem, S. M. Boyle & N. Sriranganathan. (2010). Brucellosis; A re-emerging zoonosis. Veterinary Microbiology 140 (3-4):392-398. IF=2.72 (Invited Review Article). The above manuscript is one of the most cited and most downloaded articles in Veterinary Microbiology since 2008. (1049 citations). https://doi.org/10.1016/j.vetmic.2009.06.021


4. H. Alqublan, M. N. Seleem, S. M. Boyle, & N. Sriranganathan. (2010). Tightly regulated expression system for Ochrobactrum. Current Microbiology 60 (4):242-247. IF = 1.37. https://doi.org/10.1007/s00284-009-9532-6


3. A. Ranjan, N. Pothayee, M. N. Seleem, N. Jain, N. Sriranganathan, J. S. Riffle & R. Ksimanickam. (2010). Drug delivery using novel nanoplexes against a Salmonellamouse infection model. Journal of Nanoparticle Research 12 (3):905–914. IF = 2.27. https://doi.org/10.1007/s11051-009-9641-y


2. A. Ranjan, N. Pothayee, T. P. Vadala, M. N. Seleem, E. Restis, N. Sriranganathan, J. S. Riffle & R. Kasimanickam. (2010). Efficacy of amphiphilic Development of pluronic P85 based core-shell nanostructures encapsulating gentamicin against an in-vitro Salmonella and Listeria intracellular infection model. Antimicrobial Agents and Chemotherapy 54 (8):3524-3526. IF= 4.45 . https://doi.org/10.1128/AAC.01522-09


1. N. Surendran, K. Zimmerman , M. N. Seleem, N. Sriranganathan, S. M. Boyle, E. M. Hiltbold, H. Lawler, B. Heid & S. Witonsky. (2010). Ability of Brucella abortus rough vaccine strains to elicit DC and innate immunity in lung using a murine respiratory model. Vaccine 28 (43):7009-7015. IF= 3.48. https://doi.org/10.1016/j.vaccine.2010.08.039https://doi.org/10.1111/j.1574-6968.2008.01358.x

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